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Senta Georgia (Photo by Cristy Lytal)

What I’m Reading: Top pick from stem cell faculty member Senta Georgia

Earlier this year, a team at the Karolinska Institute published a paper that profiled gene activity in single cells from human embryos created in the context of in vitro fertilization. Now this …

Qi-Long Ying (Photo by Cristy Lytal)

What I’m Reading: Top pick from stem cell faculty member Qi-Long Ying

In a recent study published in Cell Stem Cell, Joshua Black and colleagues demonstrated that skin cells are converted into neurons using a powerful tool called CRISPR/Cas9 to concurrently modify and activate …

Wange Lu (Photo by Chris Shinn)

What I’m reading: Top pick from stem cell faculty member Wange Lu

Our genetic material is packed into the nucleus of the cell, but is the packing process random or organized in some way? In a recent study published in Cell Stem Cell, Krijger …

Megan McCain (Photo by Will Taylor)

Megan McCain receives American Heart Association Faculty Award

Megan McCain has received a 2016 Scientist Development Grant from the American Heart Association. The three-year, $231,000 grant supports highly promising early career scientists in cardiovascular and stroke research. McCain—Gabilan Assistant Professor …

Francesca Mariani (Photo by Chris Shinn)

What I’m reading: Top pick from stem cell faculty member Francesca Mariani

In a recent study in the journal Cell, Kyle Loh and colleagues in Irving Weissman’s group established a rapid protocol for converting human pluripotent stem cells into mesoderm—the progenitors for heart, skeleton, …

Researchers have found a protein that may help with the brain’s recovery from a stroke. (Illustration courtesy of Shutterstock)

There’s hope for reversing stroke-induced long-term disability

Permanent brain damage from a stroke may be reversible thanks to a developing therapeutic technique, a USC-led study has found. The novel approach combines transplanted human stem cells with a special protein …

Rong Lu (Photo by Cristy Lytal)

What I’m reading: Top pick from stem cell faculty member Rong Lu

In a recent issue of Nature, Fan Zhou, Bing Liu and colleagues present their work on tracing the developmental origin of blood stem cells, also known as hematopoietic stem cells (HSCs), in …

Joseph T. Rodgers (Photo by Cristy Lytal)

What I’m reading: A top pick from stem cell faculty member Joseph T. Rodgers

In a recent issue of Science, Jay Shendure, Alexander Schier and colleagues present an extraordinarily powerful new approach to trace the lineage of cells as they divide within an organism.

From left, Andy McMahon and Gage Crump (Photos by Phil Channing and the Crump Lab)

What I’m reading: Top picks from stem cell faculty members Andy McMahon and Gage Crump

Andy McMahon: Leigh Turner and Paul Knoepfler present a disturbing report in Cell Stem Cell on the growth of businesses marketing stem cell interventions in the US. Los Angeles is one “stem …

From top: Dion Dickman (left), Megan McCain and Justin Ichida; Rong Lu (left) and Keyue Shen (Photos by Cristy Lytal)

USC Stem Cell researchers receive the inaugural Broad Innovation Awards

Two teams of scientists have won the inaugural Eli and Edythe Broad Innovation Awards in Stem Cell Biology and Regenerative Medicine at USC. This year’s competition provides $120,000 each to the teams …

Stem cells self-organize to form a hollow ball of cells. (Image by In Kyoung Mah and Francesca Mariani)

A gene called Prkci helps organize organisms and their organs

A gene called Prkci can point cells in the right direction, according to a new study in Developmental Biology. In the study, USC Stem Cell researcher In Kyoung Mah from the laboratory …

Clockwise from top left: Study authors Casey Brewer, Elizabeth Chu, Rong Lu and Mike Chin (Photos by Cristy Lytal)

Dose of transplanted blood-forming stem cells affects their behavior

Unlike aspirin, bone marrow doesn’t come with a neatly printed label with dosage instructions. However, a new study published in Cell Reports provides clues about how the dose of transplanted bone marrow …

Malcolm Snead (Photo courtesy of the Ostrow School of Dentistry of USC)

Amplifying cell signals for potentially lower cost stem cell interventions

Editor’s Note: USC Stem Cell principal investigators Malcolm Snead and Yan Zhou were among the authors of “Supramolecular Nanofibers Enhance Growth Factor Signaling by Increasing Lipid Raft Mobility,” published on April 12, …

Keynote speaker Brigid Hogan presents at the Hastings Center for Pulmonary Research inaugural symposium March 11. (Photo courtesy of HSC News)

Hastings Center for Pulmonary Research holds inaugural symposium

Physicians and leading scientists from across the country gathered recently to celebrate the inauguration of the Keck School of Medicine of USC’s Hastings Center for Pulmonary Research. More than 100 people attended …

3-D printed Cas9 enzyme that snips a DNA sequence at a location identified by CRISPR. (Photo courtesy of the NIH 3D Print Exchange, National Institutes of Health)

USC Stem Cell scientists enter the conversation about CRISPR

CRISPR-Cas9 is a gene-editing technique that enables scientists to disable, replace or modify sections of DNA. It allows for unprecedented precision and speed in the field of genome editing. It has been used to …

From left, Hsiang-Ying (Sherry) Lee, Sergei Doulatov, Leonardo Morsut, Alexander Pollen and Joan Font-Burgada (Photo by Cristy Lytal)

USC Stem Cell mini-symposium introduces next-generation researchers

The next generation of scientists is turning to stem cells to advance our understanding of systems ranging from the blood to the brain, from the liver to the lungs. Six of these …

Qi-Long Ying (Photo by Cristy Lytal)

Scientists Qi-Long Ying and Austin Smith win the 2016 McEwen Award for Innovation

Video by Henry Liu Researchers Qi-Long Ying from USC and Austin Smith from the University of Cambridge have won the 2016 McEwen Award for Innovation, the highest honor bestowed by the International …

Motor neurons derived from an ALS patient (Image courtesy of the Ichida Lab)

USC announces winners of the Audrey E. Streedain Regenerative Medicine Initiative Awards

Two collaborative teams within USC Stem Cell are developing new approaches that could eventually help patients with heart disease, frontotemporal dementia and amyotrophic lateral sclerosis (ALS). The teams are the winners of …

Paula Cannon (Photo by Don Milici)

USC and Sangamo researchers advance genome editing of blood stem cells

Genome editing techniques for blood stem cells just got better, thanks to a team of researchers at USC and Sangamo BioSciences. In an upcoming study in Nature Biotechnology, co-first authors Colin M. …

The gene Prkci promotes the generation of differentiated cells (red). However if Prkci activity is reduced or absent, neural stem cells (green) are promoted. (Image by In Kyoung Mah)

A Prkci gene keeps stem cells in check

When it comes to stem cells, too much of a good thing isn’t wonderful: producing too many new stem cells may lead to cancer; producing too few inhibits the repair and maintenance …