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Zebrafish heart with coronary vessels (Image courtesy of Ellen Lien/Children's Hospital Los Angeles)

Ching-Ling (Ellen) Lien awarded $1.7 million to study heart regeneration

Ching-Ling (Ellen) Lien, an investigator at The Saban Research Institute of Children’s Hospital Los Angeles (CHLA) and principal investigator with USC Stem Cell, has been awarded nearly $1.7 million, over a four …

Jian Xu (Photo courtesy of the Ostrow School of Dentistry of USC)

Researcher Jian Xu earns accolades for cell fate studies

Basic science can often be far from basic—especially for Jian Xu, who believes cells are kind of like people. “In simple terms, we look at how cells determine their own fate,” said …

Amy Ryan (Firth)

USC Stem Cell scientist Amy Firth named finalist for the British Council’s 2017 Alumni Awards

As a USC Stem Cell scientist studying lung disease, Amy Firth has done her alma mater proud. An alumna of the University of Bath, Firth has earned a coveted place as a …

Valter Longo (Photo by Dietmar Quistorf)

Scientifically-designed fasting diet lowers risks for major diseases

What if you could lose weight and reduce your risk of life-threatening disease without any changes in what you eat—other than a five-day special diet once every few months? That’s what happened …

Keyue Shen

Beating the spread

Cancer cells are like normal cells, only trickier. They carry genetic mutations that can hoodwink their surroundings to favor their growth. Using biologically inspired in vitro models, Keyue Shen, an assistant professor …

Amy Ryan (Firth) (Photo by Cristy Lytal)

What I’m reading: Stem cell faculty member Amy Firth offers a top pick

To understand organ development, maintenance and repair, and to model disease, tissue engineering can enable unique experimental approaches. In a recent study in the journal Biomaterials, Daniel Tschumerplin’s laboratory at the Mayo …

Rong Lu (Photo by Cristy Lytal)

What I’m reading: Top picks from stem cell faculty

In a recent issue of Nature, Philipp S. Hoppe and colleagues present their work on how blood-forming cells, called hematopoietic progenitors, commit to becoming particular blood cell types.

Adnan Chowdhury (Photo by Cristy Lytal)

Hearst Fellow Adnan Chowdhury studies how stem cells respond to infection

Few researchers have studied how hematopoietic stem cells respond to infection—even though these are the stem cells that give rise to the full battery of specialized immune cells, such as T cells …

Amy Ryan (Firth) (Photo courtesy of the Keck School of Medicine of USC)

What I’m Reading: Top pick from stem cell faculty member Amy Firth

Cells regulate their gene activity and differentiation by “methylating” DNA—adding carbon and hydrogen atoms to modify the DNA code. In a recent Cell publication, researchers from the Jaenisch laboratory used a precise …

Senta Georgia (Photo by Cristy Lytal)

What I’m Reading: Top pick from stem cell faculty member Senta Georgia

Earlier this year, a team at the Karolinska Institute published a paper that profiled gene activity in single cells from human embryos created in the context of in vitro fertilization. Now this …

Qi-Long Ying (Photo by Cristy Lytal)

What I’m Reading: Top pick from stem cell faculty member Qi-Long Ying

In a recent study published in Cell Stem Cell, Joshua Black and colleagues demonstrated that skin cells are converted into neurons using a powerful tool called CRISPR/Cas9 to concurrently modify and activate …

Wange Lu (Photo by Chris Shinn)

What I’m reading: Top pick from stem cell faculty member Wange Lu

Our genetic material is packed into the nucleus of the cell, but is the packing process random or organized in some way? In a recent study published in Cell Stem Cell, Krijger …

Megan McCain (Photo by Will Taylor)

Megan McCain receives American Heart Association Faculty Award

Megan McCain has received a 2016 Scientist Development Grant from the American Heart Association. The three-year, $231,000 grant supports highly promising early career scientists in cardiovascular and stroke research. McCain—Gabilan Assistant Professor …

Francesca Mariani (Photo by Chris Shinn)

What I’m reading: Top pick from stem cell faculty member Francesca Mariani

In a recent study in the journal Cell, Kyle Loh and colleagues in Irving Weissman’s group established a rapid protocol for converting human pluripotent stem cells into mesoderm—the progenitors for heart, skeleton, …

Researchers have found a protein that may help with the brain’s recovery from a stroke. (Illustration courtesy of Shutterstock)

There’s hope for reversing stroke-induced long-term disability

Permanent brain damage from a stroke may be reversible thanks to a developing therapeutic technique, a USC-led study has found. The novel approach combines transplanted human stem cells with a special protein …

Rong Lu (Photo by Cristy Lytal)

What I’m reading: Top pick from stem cell faculty member Rong Lu

In a recent issue of Nature, Fan Zhou, Bing Liu and colleagues present their work on tracing the developmental origin of blood stem cells, also known as hematopoietic stem cells (HSCs), in …

Joseph T. Rodgers (Photo by Cristy Lytal)

What I’m reading: A top pick from stem cell faculty member Joseph T. Rodgers

In a recent issue of Science, Jay Shendure, Alexander Schier and colleagues present an extraordinarily powerful new approach to trace the lineage of cells as they divide within an organism.

From left, Andy McMahon and Gage Crump (Photos by Phil Channing and the Crump Lab)

What I’m reading: Top picks from stem cell faculty members Andy McMahon and Gage Crump

Andy McMahon: Leigh Turner and Paul Knoepfler present a disturbing report in Cell Stem Cell on the growth of businesses marketing stem cell interventions in the US. Los Angeles is one “stem …

From top: Dion Dickman (left), Megan McCain and Justin Ichida; Rong Lu (left) and Keyue Shen (Photos by Cristy Lytal)

USC Stem Cell researchers receive the inaugural Broad Innovation Awards

Two teams of scientists have won the inaugural Eli and Edythe Broad Innovation Awards in Stem Cell Biology and Regenerative Medicine at USC. This year’s competition provides $120,000 each to the teams …

Stem cells self-organize to form a hollow ball of cells. (Image by In Kyoung Mah and Francesca Mariani)

A gene called Prkci helps organize organisms and their organs

A gene called Prkci can point cells in the right direction, according to a new study in Developmental Biology. In the study, USC Stem Cell researcher In Kyoung Mah from the laboratory …