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Impromptu McMahon lab meeting; featured image for USC honors stem cell leader Andy McMahon with a lifetime achievement award

USC honors stem cell leader Andy McMahon with a lifetime achievement award

The award recognizes McMahon’s career advancing developmental biology and building scientific communities, including USC Stem Cell. As a pioneer in developmental biology and founder of USC Stem Cell, Andy McMahon, PhD, FRS, …

Red indicates mouse embryonic stem cells and green indicates mouse epiblast stem cells. The two cell types were co-cultured under GSK3α inhibition and maintained their distinct identities. (Image by Duo Wang/Ying Lab/USC Stem Cell); featured image for A “stemness checkpoint” helps control stem cell identity

A “stemness checkpoint” helps control stem cell identity

Building on the concept that blocking differentiation into specialized cell types maintains stem cells, USC and NIH scientists identify GSK3α as a checkpoint across diverse stem cell types. A study published in …

Clockwise from top left, Paula Cannon, Alan Epstein, Heinz-Josef Lenz and Bodour Salhia (Photos by Don Milici and Ricardo Carrasco III); featured image for Four Keck School of Medicine of USC researchers elected as senior members of the National Academy of Inventors

Four Keck School of Medicine of USC researchers elected as senior members of the National Academy of Inventors

Honorees have created technologies for fighting cancer and other diseases by harnessing the immune system, DNA and the mechanisms that control gene expression. The National Academy of Inventors (NAI), a nonprofit member …

The new joint department will accelerate health care innovation. (USC Photos); featured image for USC announces joint biomedical engineering department, bridging medical and engineering schools

USC announces joint biomedical engineering department, bridging medical and engineering schools

Building on decades of collaboration between the USC Viterbi School of Engineering and the Keck School of Medicine of USC, the department reimagines the expansion of biomedical engineering into medicine. The Keck …

Megan McCain's lab (Photo by Chris Shinn)

USC launches a new Center for Stem Cell Engineering on the Health Sciences Campus

A collaboration between the Keck School of Medicine of USC and the USC Viterbi School of Engineering, the center will use stem cell engineering to uncover disease mechanisms and advance new therapies. …

An implantable retinal patch for restoring vision is one of the university’s most cited examples of therapeutic success. (Illustration/aDerek Brahney); featured image for From lab to launch: Inside USC’s fast-growing ecosystem of health startups

From lab to launch: Inside USC’s fast-growing ecosystem of health startups

From patches that restore vision to compounds that kill brain tumors, drug and device discoveries by USC researchers are reaching patients faster than ever before. Ten years ago, two pediatric heart specialists …

Chuck Murry in the third-grade class at Vermont Avenue Elementary School (Photo by DJ Kast); featured image for USC Stem Cell’s Chuck Murry shows heart for local third-graders through the medical and cancer STEM programs

USC Stem Cell’s Chuck Murry shows heart for local third-graders through the medical and cancer STEM programs

USC’s Medical STEM Program brings pig hearts, pulse oximeters, and a world of possibility to local third graders. At Vermont Avenue Elementary School, a class of third graders stared wide-eyed as Chuck …

Biomedical engineers at USC Viterbi are using ultrasound to trick tumor cells into effectively painting a target on their own backs, enabling more powerful treatments. Image/ChatGPT.; featured image for Tricking tumors into marking themselves for destruction

Tricking tumors into marking themselves for destruction

New research from the USC Viterbi School of Engineering harnesses focused ultrasound to reprogram solid tumors, making them more effective targets for immune cells. USC biomedical engineers have found a way to …

Cellular extracellular vessicles; featured image for What if cells could talk and fight heart disease?

What if cells could talk and fight heart disease?

USC Viterbi’s Chung Lab has engineered a naturally derived particle for powerful therapies against cardiovascular and kidney diseases. Have you seen the latest EV models? Nope, not the Tesla Model 3. Think …

The National Institute on Aging has awarded a $6.5 million, five-year grant to Cedars-Sinai, USC and UCLA to create the Los Angeles Claude D. Pepper Older Americans Independence Center. (USC Photo/Nat Avunjian); featured image for New NIA-funded center to help older adults live longer, healthier lives

New NIA-funded center to help older adults live longer, healthier lives

A new Los Angeles research hub will take on one of today’s most pressing challenges: helping people live not just longer, but healthier and more independent lives as they age. The National …

Cancer associated cells identified by the rare event detector in patients with breast cancer, image courtesy of the Oberai and Kuhn research groups at USC.; featured image for Researchers invent new AI tool to automate detection of cancer in blood samples

Researchers invent new AI tool to automate detection of cancer in blood samples

Innovation detects cancer cells in blood samples (liquid biopsies) in as little as 10 minutes and identifies hard-to-find cells without humans in-the-loop. When cancer spreads, tiny amounts of cells can break away …

Elena Vasileva, PhD, and James Amatruda, MD, PhD; featured image for Discovery may point to cell of origin for Ewing sarcoma

Discovery may point to cell of origin for Ewing sarcoma

New study suggests that neural crest cells are reprogrammed into tumor-forming cells, reshaping the understanding of this childhood cancer. For decades, scientists have been puzzled by two enduring mysteries around Ewing sarcoma. …

From left, Denis Evseenko and Toby Maher; featured image for USC physician-scientists Denis Evseenko and Toby Maher win $3.2 million grant from the National Institute on Aging to develop regenerative drug for idiopathic pulmonary fibrosis

USC physician-scientists Denis Evseenko and Toby Maher win $3.2 million grant from the National Institute on Aging to develop regenerative drug for idiopathic pulmonary fibrosis

It might start with a shortness of breath that’s easily dismissed as getting older or needing more exercise. But for the nearly 3 million patients with idiopathic pulmonary fibrosis (IPF), this subtle …

Genetically engineered chimeric antigen receptor immune cell (image courtesy of iStock); featured image for Next-generation CAR T cells could expand solid cancer treatment options

Next-generation CAR T cells could expand solid cancer treatment options

Using cell cultures and animal models, researchers from the USC Norris Comprehensive Cancer Center at Keck School of Medicine of USC showed that innovative ways to further engineer CAR T cells can …

Embryonic stem cells from a Barred Plymouth Rock chicken (Image by Xi Chen/Ying Lab/USC Stem Cell); featured image for USC Stem Cell-led study generates authentic embryonic stem cells from birds

USC Stem Cell-led study generates authentic embryonic stem cells from birds

Scientists discover that egg yolk is a key to establishing authentic embryonic stem cells from chickens and seven other avian species, as reported in Nature Biotechnology. Egg whites may be perfect for …

; featured image for USC Stem Cell students and trainees win $15,000 collaborative research grants

USC Stem Cell students and trainees win $15,000 collaborative research grants

When learning to become a great scientist, the most important lesson might be how to collaborate. To encourage this essential skill, for the past decade, USC Stem Cell has awarded one-year challenge …

Guanyi Huang (Photo courtesy of Guanyi Huang); featured image for Meet USC’s CIRM Scholar Alumni: Guanyi Huang, Associate Principal Scientist at Merck

Meet USC’s CIRM Scholar Alumni: Guanyi Huang, Associate Principal Scientist at Merck

Guanyi Huang, associate principal scientist at Merck, has often found himself in the right place at the right time. The son of a middle school math teacher and computer science professor-turned-entrepreneur, Huang …

Suhasni Gopalakrishnan at the Base Torres del Paine in Patagonia, Chile. (Photo by Arvind Baskaran); featured image for Meet USC’s CIRM Scholar Alumni: Suhasni Gopalakrishnan, Director at Allogene Therapeutics

Meet USC’s CIRM Scholar Alumni: Suhasni Gopalakrishnan, Director at Allogene Therapeutics

“I feel like I’m a person who goes with the flow,” said Suhasni Gopalakrishnan, Director at Allogene Therapeutics in San Francisco. Going with the flow has led Gopalakrishnan to many fascinating places. …

Noah Merin (Photo courtesy of Cedars-Sinai); featured image for Meet USC’s CIRM Scholar Alumni: Noah Merin, Assistant Professor at Cedars-Sinai

Meet USC’s CIRM Scholar Alumni: Noah Merin, Assistant Professor at Cedars-Sinai

For physician-scientist Noah Merin, the form of stem cell transplantation known as bone marrow transplantation remains the “coolest thing in medicine” and the focus of his career. “I do bone marrow transplantation …

Cardiovascular disease is the leading cause of death in the United States. (Image courtesy of Pexels); featured image for New nanoparticle weapon in the fight against cardiovascular and kidney disease

New nanoparticle weapon in the fight against cardiovascular and kidney disease

The Chung Lab has engineered a new therapeutically enhanced, naturally derived particle for powerful gene therapies to tackle our most significant health challenges. Cardiovascular disease and kidney disease are two of the …