New USC/CHLA cGMP Lab opens to accelerate next-generation cell therapy
A new laboratory designed to advance early-stage research into lifesaving, commercially viable therapies was celebrated on the USC Health Sciences Campus Tuesday night. Housed at the USC Norris Comprehensive Cancer Center, the …
Why multipotent progenitor cells matter for patients receiving bone marrow transplants
When patients receive bone marrow transplants, they are infused with complex admixtures of many different cell types with the power to regenerate their blood and immune systems. In a new study in …
Saving lives: Heart attack on a chip
Megan McCain has always enjoyed building and fixing things. She also has long been fascinated by cells in the human body and how they work together to achieve important tasks, like how …
Scientists feel the sand between their toes at the retreat for USC’s stem cell department
A pair of young scientists picked up a piece of driftwood and thoughtfully traced a series of letters in the wet sand of Ventura Beach. The word “microglia”—referring to the immune cells …
USC and CHLA awarded $8 million to expand access to cell and gene therapy clinical trials
The California Institute for Regenerative Medicine (CIRM), the state’s stem cell agency, has awarded a five-year, $8 million grant to the Keck School of Medicine of USC and Children’s Hospital Los Angeles (CHLA). …
This mouse can’t keep a secret about the “secretome”
The “secretome” refers to proteins that are secreted by a cell, a tissue or an organism. In a new study published in Open Biology, USC Stem Cell scientist Andy McMahon and his …
Study of mouse immune cells highlights differences between males and females
A new data set collected by USC Leonard Davis School of Gerontology researchers provides an important new resource for studying differences in immune system function by age and sex. The study, published …
How did vertebrates first evolve jaws?
Five-hundred million years ago, it was relatively safe to go back in the water. That’s because creatures of the deep had not yet evolved jaws. In a new pair of studies in …
USC faculty member Rong Lu: Providing insights into stem cell biology in the context of aging and disease
Rong Lu is an associate professor of stem cell biology and regenerative medicine, biomedical engineering, medicine, and gerontology at USC. She joins George Shannon, faculty member and host of the podcast “Lessons …
Where are they now? Stem cell master’s program alumna Clare Yarka, a Scientist at Instil Bio
In this series of alumni profiles, we highlight graduates of USC’s master of science program in stem cell biology and regenerative medicine. Our accomplished alumni have pursued many different paths—ranging from a …
Communicating science visually: Mukund Iyer, MaryAnne Achieng and Stephanie Chang win the 2022 Winter BioRender contest
For his graphic on immune cell function in the brain, Mukund Iyer took first place in the Winter 2021 BioRender Illustration competition for his schematic of breast cancer cells’ entry through the …
Stem cell scientists explore the mysteries of regeneration at the Junior Faculty Candidate Seminar and Symposium
How can we regenerate tissues that are damaged, lost or diseased in the human body? This was the central question driving the four scientists who presented their research at the Junior Faculty …
For USC Stem Cell faculty member Rong Lu, science is in her blood
When Rong Lu joined USC as an assistant professor of stem cell biology and regenerative medicine in 2014, she knew that earning tenure would figuratively require blood, sweat and tears. But after …
How alike are the cancer cells from a single patient?
Even within a single patient with cancer, there is a vast diversity of individual tumor cells, which display distinct behaviors related to growth, metastasis, and responses to chemotherapy. To carry out these …
Drug-like molecule points to novel strategies for cancer therapy
A decade ago, genome sequencing revealed a big surprise: about 50 percent of human cancers are linked to mutations in what are known as epigenetic regulators, which control the activity of genes. …
USC Stem Cell: An incubator for medicine of the 21st century
Just over a decade ago, USC was a university with a few scattered stem cell biologists, and a vision for total transformation. The university was committed to designing a unique “incubator” for …
Cycles of a fasting-mimicking diet help mice live longer, healthier
While many diets have been studied for effectiveness in preventing obesity and heart disease in both mice and humans, research on the effects and benefits of short, periodic cycles of fasting on obesity and heart health are lacking. In a new USC study on the health effects of a low-calorie diet that mimics …
Bérénice Benayoun receives prestigious investigator-focused grant
The Maximizing Investigators’ Research Award directly supports scientists, providing stability, flexibility and more opportunities for breakthroughs. The National Institute of General Medical Sciences has awarded an R35 Maximizing Investigators’ Research Award (MIRA) …
Top scientists and research institutions propose improvements to cell- and gene-based therapy development
Led by a USC cell and gene therapy researcher, an international coalition calls for more transparency and reproducibility in research and development of breakthrough treatments. Scientists around the world are achieving significant …
Study highlights differences in immune cell function between male and female mice
A new USC study of a common, yet poorly understood type of white blood cell reveals the human immune cell’s response to pathogens differs greatly by sex and by age. In this mouse study, males proved much more susceptible to a condition called sepsis than females. However, the scientists also found that the female disease-defense system is …