USC and Sangamo researchers advance genome editing of blood stem cells
Genome editing techniques for blood stem cells just got better, thanks to a team of researchers at USC and Sangamo BioSciences. In an upcoming study in Nature Biotechnology, co-first authors Colin M. …
A Prkci gene keeps stem cells in check
When it comes to stem cells, too much of a good thing isn’t wonderful: producing too many new stem cells may lead to cancer; producing too few inhibits the repair and maintenance …
Chang Stem Cell Engineering Facility brings gene editing to USC and beyond
Once the stuff of science fiction, genetic engineering is now offered on a fee-for-service basis at USC. On September 19, USC Stem Cell faculty and staff welcomed their supporters, the Chang and …
The road to a cure for HIV/AIDS
Something wonderful sometimes happens when scientists and the public get together to talk about research. All the jargon, all the technical language falls away, and it becomes instead a conversation between the …
Researchers create promising new model for lung injury repair
Researchers at Children’s Hospital Los Angeles and The Saban Research Institute of CHLA have created a dynamic functional mouse model for lung injury repair, a tool that will help scientists explain the …
Stem cell transplantation for children with rare form of leukemia improves outcomes
Researchers in the Division of Hematology, Oncology and Blood & Marrow Transplantation at Children’s Hospital Los Angeles have shown greatly improved outcomes in using stem cell transplantation to treat patients with a …
USC Stem Cell researchers poke around for blood genes
Even though the transplantation of blood stem cells, also known as bone marrow, has saved many lives over many decades, the genes that control the number or function of blood stem cells …
USC postdocs win Doerr Stem Cell Challenge Grants
Just as there are times when two heads are better than one, there are times when two labs are better than one. Thanks to the new Doerr Stem Cell Challenge Grants, teams …
Diet that mimics fasting appears to slow aging
Want to lose abdominal fat, get smarter and live longer? New research led by USC Stem Cell principal investigator Valter Longo shows that periodically adopting a diet that mimics the effects of …
Tiny heart, big promise
The heart has its own dedicated blood supply, with coronary arteries that supply oxygen-rich blood to the heart and cardiac veins that remove deoxygenated blood. This system of vessels nourishes the heart, …
Take a tour of USC’s stem cell research center
Video by Alric Devotta Director Andy McMahon leads a tour of the Eli and Edythe Broad CIRM Center for Regenerative Medicine and Stem Cell Research at USC.
Promising new target may treat pulmonary fibrosis
By uncovering the mechanism by which fibrous tissue cells in the lung multiply, researchers at The Saban Research Institute of Children’s Hospital Los Angeles (CHLA), along with colleagues in Mexico and Canada, …
USC mini-symposium showcases the next generation of top stem cell scientists
Obesity, narcolepsy, leukemia and muscle injuries have at least one thing in common: they are engaging the next generation of top stem cell scientists. Five of these scientists presented their research at …
CIRM-funded clinical trial aimed at blocking HIV/AIDS in people gets the go ahead
An innovative therapy using a patient’s own stem cells, modified to resist infection with the AIDS virus, has been given approval by the Food and Drug Administration (FDA) to begin a clinical …
“Million-dollar ideas” seminar
At a special seminar on February 24, USC Stem Cell Principal Investigators discussed their “million-dollar ideas” for creating new tools and technologies to usher in the era of regenerative medicine. They shared …
Three USC researchers win $4.3 million in awards from California’s stem cell agency
Three scientists from Keck Medicine of USC have won grants exceeding $4.3 million from the California Institute for Regenerative Medicine (CIRM) for research that includes creating a temporary liver for patients, finding …
New option benefits patients needing bone marrow transplants
Keck Medical Center of USC is offering a new option for patients who need bone marrow (also called stem cell) transplants, but have not found a match. Haploidentical transplants allow patients who …
Protein-based therapy shows promise against resistant leukemia
Resistance of leukemia cells to contemporary chemotherapy is one of the most formidable obstacles to treating acute lymphoblastic leukemia (ALL), the most common form of childhood cancer. Now researchers at Children’s Hospital …
Mammalian heart regenerative capacity depends on severity of injury
A new study by researchers at Children’s Hospital Los Angeles (CHLA) has shown that neonatal mouse hearts have varying regenerative capacities depending upon the severity of injury. Using cryoinjury — damaging the …
Min Yu and Heinz-Josef Lenz seek to stop cancer in its tracks
Heinz-Josef Lenz and Min Yu both know that a cancer cell in motion doesn’t stay in motion. It comes to rest and spreads cancer. After detaching from the primary tumor and traveling …