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Megan McCain (Photo by Michelle Henry)

Megan McCain wears her heart on a chip

Video by Elizabeth Bayne Megan McCain first saw a real human heart her junior year of college. She held it in her hands – dark red, squishy, the size of a fist. …

Zea Borok

Zea Borok elected to American Association of Physicians

Zea Borok, MD, USC Stem Cell principal investigator and professor of medicine and of biochemistry and molecular biology at the Keck School of Medicine of USC, has been elected to membership in …

George Ban-Weiss, Maryam Shanechi and Megan McCain, from left (Photos courtesy of USC Viterbi)

Megan McCain and colleagues make MIT list of 35 Innovators Under 35

The annual MIT Technology Review list of 35 Innovators Under 35 includes three USC Viterbi School of Engineering faculty members — including Megan McCain, principal investigator with USC Stem Cell. Professors McCain and …

Multi-well plate (Image courtesy of the National Institutes of Health)

USC Stem Cell and the USC Norris Comprehensive Cancer Center accelerate drug discovery

Three teams of USC stem cell researchers have won a coveted prize — the opportunity to test 3,000 drug candidates or chemicals for the potential to help patients. Two teams will focus …

Andy McMahon (Photo by Phil Channing)

Andy McMahon and USC Stem Cell: From discoveries to cures

Video by Little Pictures How do fingers become fingers and not toes? How does the brain generate the correct number of neurons? How do the kidneys branch into the complex and elegant …

Valter Longo (Photo by Dietmar Quistorf)

Fasting triggers stem cell regeneration of damaged, old immune system

In the first evidence of a natural intervention triggering stem cell-based regeneration of an organ or system, a study in the June 5 issue of Cell Stem Cell shows that cycles of …

Stem cell (Creative Commons image by Reuters)

NIH grants spur new stem cell research in the Department of Medicine

Cutbacks in National Institutes of Health (NIH) funding have made the climate for new research challenging. Three studies from investigators in the Department of Medicine at the Keck School of Medicine of …

Rong Lu and Min Yu (Photo by Cristy Lytal)

Min Yu and Rong Lu explore how one bad cell spoils the bunch

Principal investigators Min Yu, MD, PhD, and Rong Lu, PhD, had plans to collaborate long before they were both recruited to the Department of Stem Cell Biology and Regenerative Medicine at the …

The inferior alveolar nerve provides a niche for stem cells that maintain incisor homeostasis. When the nerve is severed, homeostasis is disrupted and within one month the affected incisor becomes chalky and breaks. (Photos/courtesy of Center for Craniofacial Molecular Biology)

Dental study provides wealth of stem cell details

An Ostrow School of Dentistry of USC study has uncovered new details on how bundles of nerves and arteries interact with stem cells and also showcases revolutionary techniques for following the cells …

SJ Gao (Photo courtesy of USC)

Viral molecules responsible for causing AIDS-related cancer

Using a rat stem cell model, USC researcher S. J. Gao, PhD and colleagues have identified a critical cancer-causing component in the virus that causes Kaposi’s sarcoma, the most common cancer among …

Valter Longo (Photo by Dietmar Quistorf)

Valter Longo seeks a recipe for longevity

Video by the USC Davis School of Gerontology Valter Longo, PhD, principal investigator with USC Stem Cell, is out to prove that gerontology is a young man’s game — just like rock …

From left to right: Marvin Nelson, MD, MBA, Rex Moats, PhD, Brent Polk, MD, Elizabeth Garrett, JD, Scott Fraser, PhD, Carmen Puliafito, MD, MBA (Photo courtesy of Children's Hospital Los Angeles)

USC and Children’s Hospital Los Angeles launch imaging lab for translational research

With the launch of the Translational Biomedical Imaging Lab (TBIL), investigators at the University of Southern California (USC) and The Saban Research Institute of Children’s Hospital Los Angeles moved us closer to a …

Event organizers Henry Sucov, PhD, and Ellen Lien, PhD, during Lien’s talk “Growth Factor Signaling in Heart Regeneration.” (Photo by Cristy Lytal)

Cardiovascular symposium takes the pulse of current research

Researchers addressed the leading cause of death in the U.S. at the Los Angeles Area Cardiovascular Research Symposium and Research Award Reception, which brought together the region’s cardiovascular specialists to examine the …

J. Jean Cui, PhD, tells the tale of the cancer therapeutic Xalkori. (Photo by Cristy Lytal)

Pfizer’s J. Jean Cui explains modern drug discovery

Only five percent of potential cancer drugs make it from phase I clinical trail to FDA approval, but J. Jean Cui, PhD, associate research fellow at Pfizer, beat the odds. Cui visited …

Embryonic stem cells (Image/courtesy of Qi-Long Ying)

USC researcher reveals how to better master stem cells’ fate

USC scientist Qi-Long Ying and a team of researchers have long been searching for biotech’s version of the fountain of youth — ways to encourage embryonic stem cells (ESCs) and epiblast stem …

Speakers at the first first Zilkha Mini­Symposium on Alzheimer’s Research at USC covered a variety of topics on the devastating disease. Pictured here (left to right) are Christian Pike, PhD, associate professor, USC Davis School of Gerontology; Hong-Wei Dong, MD, PhD, associate professor, department of neurology; Roberta Brinton, PhD, R. Pete Vanderveen Chair in Therapeutic Discovery & Development; Maria Carrillo, vice president, medical and scientific relations, Alzheimer’s Association; Russell Jacobs, PhD, member, Zilkha Neurogenetic Institute; Arthur W. Toga, PhD, Provost Professor of Ophthalmology, Neurology, Psychiatry and the Behavioral Sciences, Radiology and Engineering; director of the USC Institute for Neuroimaging and Informatics; Paul Thompson, PhD, professor of ophthalmology, neurology, psychiatry and the behavioral sciences, radiology and engineering; Helena Chui, MD, Raymond and Betty McCarron Chair in Neurology; Lon Schneider, MD, director, USC Alzheimer Disease Research and Clinical Center; Berislav Zlokovic, MD, PhD, director, Zilkha Neurogenetic Institute; and Scott Fraser, PhD, Provost Professor of Biological Sciences and Biomedical Engineering. (Photo by Amy E. Hamaker)

First Zilkha Alzheimer’s Mini-Symposium examines vascular system connections

Alzheimer’s disease is the sixth leading cause of death in the United States, and more than five million Americans live with the disease, according to the Alzheimer’s Association. Conquering Alzheimer’s was the …

From left, Andrew P. McMahon, director of the Eli and Edythe Broad Center for Regenerative Medicine and Stem Cell Research, with Yong Chen’s son Gary and researcher Qi-Long Ying (Photo by Cristy Lytal)

Businessman invests in stem cell research at USC

Chinese businessman Yong Chen has pledged $1 million to USC stem cell researcher Qi-Long Ying to support his future “eureka moments.” “When I talked to Mr. Chen, I told him that groundbreaking …

Neural stem cells derived from self-renewing mouse embryonic stem cells (Image courtesy of Qi-Long Ying)

A special protein helps embryonic stem cells keep their options open

In the ongoing quest to understand how embryonic stem cells (ESCs) retain their ability to differentiate into virtually any kind of cell, USC faculty member Qi-Long Ying and a team of researchers …

From left, Gage Crump, Jay R. Lieberman and Francesca Mariani (Photo by Cristy Lytal)

USC announces winners of first Regenerative Medicine Initiative awards

Three newly assembled disease teams within USC Stem Cell will take the early steps this year that might lead to future stem-cell based therapies for certain forms of deafness, bone defects and …

Wange Lu (Photo by Chris Shinn)

USC study sheds light on stem cell reprogramming

Researchers are learning how to turn regular cells into stem cells, a process called reprogramming. However, some of the mechanisms of the process remain unknown, such as why only a small proportion of the cells can be reprogrammed. Researchers have at least part of the answer: the structure of genes.