Andrew P. McMahon

Andrew P. McMahon, PhD, FRSW.M. Keck Provost and University Professor of Stem Cell Biology and Regenerative Medicine, and Biological Sciences 323-442-7847


Dr. McMahon’s laboratory explores the mechanisms that maintain stem/progenitor cells and regulate their differentiation to mature cell types of different organ systems, particularly the kidney. By combining genetic and genomic approaches with high resolution imaging, his group is aiming to obtain a deeper understanding of stem cell biology and to develop novel therapeutic strategies for regenerative medicine.

Stories

In a detailed, cell-by-cell look into the kidney, USC researchers found marked differences between the sexes. (Image courtesy of the McMahon Lab); featured image for Stem cell scientists reveal key differences in male, female kidney

Stem cell scientists reveal key differences in male, female kidney

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USC researchers have completed a detailed deconstruction of the kidney, revealing for the first time an intimate portrait of sexual differences and more in the organ. The findings could benefit 37 million …

USC Stem Cell at the world's largest stem cell conference (Photo by Sergio Bianco)

USC brings the world’s largest stem cell conference to Los Angeles

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For the first time ever, the City of Los Angeles hosted the world’s largest stem cell conference. By choosing Los Angeles as the host city for this major annual meeting, the International …

Jean Rosenbaum; featured image for France-USA Stem Cell Symposium gathers la crème de la crème

France-USA Stem Cell Symposium gathers la crème de la crème

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Science was the common language at the first France-USA Stem Cell Symposium, held at the Eli and Edythe Broad CIRM Center for Regenerative Medicine and Stem Cell Research at USC. The event …

The $10 million donation from the Eli and Edythe Broad Foundation will support the USC stem cell research center’s core facilities and training programs, enable recruitment and attract research funding. (Photo by Sam Comen); featured image for $10 million gift from Broad Foundation advances USC stem cell research on aging-associated disease

$10 million gift from Broad Foundation advances USC stem cell research on aging-associated disease

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USC’s groundbreaking stem cell research and training programs have received a major boost thanks to a $10 million gift from the Eli and Edythe Broad Foundation. The donation is part of the …

Embryonic stem cells that have differentiated into neurons (Image by In Kyoung Mah/Mariani Lab); featured image for From restoring sight to reversing brain damage, USC stem cell researchers are making life-changing discoveries

From restoring sight to reversing brain damage, USC stem cell researchers are making life-changing discoveries

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If anyone has a clear vision of the power of stem cell cures, it’s Anna Kuehl. She suffered a retina-wrecking disease that cost her much of her sight before USC physicians surgically …

Eye treated for macular degeneration; featured image for RSVP for 6/26 USC Public Symposium on a stem cell-based approach to treating age-related blindness

RSVP for 6/26 USC Public Symposium on a stem cell-based approach to treating age-related blindness

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A Public Symposium co-sponsored by USC Stem Cell and the Choi Family @ISSCCR 2019 RSVP at https://www.eventbrite.com/e/bringing-stem-cells-to-patients-treating-age-related-blindness-tickets-62892259441#tickets Program *Spanish translation available. 6:30 p.m. Registration and free food 7–8 p.m. Andrew P. McMahon, …

From left, Lina R. Nih, stem cell scientists Daniel Wagner, Unmesh Jadhav, Karthik Shehkar and Anastasia Tikhonova (Photo by Sergio Bianco); featured image for Stem cell scientists take it one cell at a time at the Junior Faculty Candidate Mini-symposium

Stem cell scientists take it one cell at a time at the Junior Faculty Candidate Mini-symposium

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Cells should be treated as individuals, according to the scientists who presented research at the Junior Faculty Candidate Mini-symposium, hosted by USC’s Department of Stem Cell Biology and Regenerative Medicine on February …

Andrew P. McMahon; featured image for McMahon named University Professor; Davies, Matarić and Pastor named Distinguished Professors

McMahon named University Professor; Davies, Matarić and Pastor named Distinguished Professors

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Interim USC President Wanda M. Austin has appointed Andrew P. McMahon as University Professor, and Kelvin J. A. Davies, Maja J. Matarić and Manuel Pastor Jr. as Distinguished Professors.

The Interdisciplinary Stem Cell Symposium sparked collaborations. (Photo by Sergio Bianco); featured image for USC researchers converge at the Interdisciplinary Stem Cell Symposium

USC researchers converge at the Interdisciplinary Stem Cell Symposium

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“The field of stem cell biology is one of our great convergence opportunities,” said USC Provost Michael Quick, addressing an audience of biologists, chemists, physicists, engineers, clinicians and many others. This diverse …

Erasing the distance (Photo by Sergio Bianco); featured image for USC Stem Cell and BCRegMed Virtual Symposium brings Canada to California

USC Stem Cell and BCRegMed Virtual Symposium brings Canada to California

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It didn’t require plane tickets to bring together scientists from USC Stem Cell in Los Angeles and BCRegMed in Vancouver. During October’s Virtual Symposium, videoconferencing technology enabled these scientists to share ideas …

Andy McMahon (Photo by Phil Channing); featured image for USC Stem Cell scientist Andy McMahon and collaborators tune into the organ concert

USC Stem Cell scientist Andy McMahon and collaborators tune into the organ concert

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Every minute of every day, your organs are using a complex language to communicate with each other about the basic physiological processes necessary for life—everything from blood pressure regulation to pH balance …

Note to self (Photo by Sergio Bianco); featured image for At the retreat for USC’s stem cell department, the students become the masters

At the retreat for USC’s stem cell department, the students become the masters

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Students and trainees took center stage at the annual retreat for USC’s Department of Stem Cell Biology and Regenerative Medicine. They presented their latest research to the 180 stem cell scientists who …

Developing human nephron, the filtering unit of the kidney (Image by Nils O. Lindström and Tracy Tran/McMahon Lab); featured image for From perfectly punctual to fashionably late, it takes all kinds to build a kidney

From perfectly punctual to fashionably late, it takes all kinds to build a kidney

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Running early or running late can have big consequences—especially when it comes to the progenitor cells involved in human kidney development. According to a new study in Developmental Cell from the USC …

Kidney (Image by Lori O'Brien/Andy McMahon Lab, illustration by Mira Nameth)

Growing hope: New organs? Not yet, but stem cell research is getting closer

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If you lose a limb, it’s lost for life. If you damage a kidney, you won’t grow a new one. And if you have a heart attack, the scars are there to …

Justin Ichida (Photo by Ben Gibbs); featured image for USC Stem Cell scientist Justin Ichida named inaugural Richard N. Merkin Scholar

USC Stem Cell scientist Justin Ichida named inaugural Richard N. Merkin Scholar

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In USC’s Department of Stem Cell Biology and Regenerative Medicine, half of the faculty members are assistant professors, poised at the threshold of their careers in biomedical research. One of these promising …

From left, stem cell researchers Andres Matias Lebensohn, Maxwell Z. Wilson, Seth Shipman, Pulin Li and Yejing Ge (Photo by Cristy Lytal); featured image for At USC’s Junior Faculty Mini-Symposium, stem cell scientists build to understand

At USC’s Junior Faculty Mini-Symposium, stem cell scientists build to understand

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When physicist Richard Feynman died in 1988, he left a message scrawled across his chalkboard: “What I cannot create, I do not understand.” Twenty years later, scientists in a very different field …

At an early stage, a nephron forming in the human kidney generates an S-shaped structure. Green cells will generate the kidneys’ filtering device, and blue and red cells specialized regions responsible for distinct nephron activities. (Image courtesy of Stacy Moroz and Tracy Tran/McMahon Lab); featured image for Never accept a kidney donation from a mouse

Never accept a kidney donation from a mouse

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Researchers are hard at work building mini-kidneys from human cells—using blueprints mostly drawn from lab mice. But mouse kidneys differ from their human counterparts in more than mere scale, as detailed by …

Larry Goldstein, the director of the stem cell program at the University of California, San Diego, and keynote speaker at the retreat for USC’s Department of Stem Cell Biology and Regenerative Medicine (Photo by Cristy Lytal); featured image for Scientists get into detail at the retreat for USC’s stem cell department

Scientists get into detail at the retreat for USC’s stem cell department

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“The process of disease is about detail,” said Larry Goldstein, the director of the stem cell program at the University of California, San Diego, and keynote speaker at the retreat for USC’s …

Injury-related damage in a mouse chronic kidney disease model (Image by Jing Liu/McMahon Lab); featured image for The Broad Foundation awards $1 million to early-stage stem cell research projects

The Broad Foundation awards $1 million to early-stage stem cell research projects

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The Eli and Edythe Broad Foundation has awarded two $125,000 grants to early-stage scientific investigations at USC’s stem cell research center. The projects are among eight winners of the $1 million Fund …

Richard Lopez (Photo by Cristy Lytal); featured image for High school student Richard Lopez gets an early start with stem cell science

High school student Richard Lopez gets an early start with stem cell science

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Even though Richard Lopez is still in high school, he can already tell you a thing or two about the ureteric bud, the metanephric mesenchyme and the developing kidney. More impressively, he …

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Andrew P. McMahon, PhD, FRS