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Skeletal staining of the lower face of a zebrafish, with cartilage in blue, and bones and teeth in red. (Image by Pengfei Xu/Crump Lab); featured image for A Fox code for the face

A Fox code for the face

In the developing face, how do stem cells know whether to become cartilage, bones or teeth? To begin to answer this question, scientists from the USC Stem Cell laboratory of Gage Crump …

Developing human nephron, the filtering unit of the kidney (Image by Nils O. Lindström and Tracy Tran/McMahon Lab); featured image for From perfectly punctual to fashionably late, it takes all kinds to build a kidney

From perfectly punctual to fashionably late, it takes all kinds to build a kidney

Running early or running late can have big consequences—especially when it comes to the progenitor cells involved in human kidney development. According to a new study in Developmental Cell from the USC …

A healthy T cell (Image courtesy of the National Institute of Allergy and Infectious Diseases); featured image for When it comes to balancing the immune system, some blood stem cells are better than others

When it comes to balancing the immune system, some blood stem cells are better than others

In your body, blood stem cells produce approximately 10 billion new white blood cells, which are also known as immune cells, each and every day. Even more remarkably, if some of these …

Metastatic breast cancer cells (yellow) interacting with macrophages (magenta) (Image by Oihana Iriondo/Yu Lab); featured image for Particle shows promise for treating the most deadly type of breast cancer

Particle shows promise for treating the most deadly type of breast cancer

USC Stem Cell researchers from the laboratory of Min Yu have positive news for patients with triple-negative breast cancer (TNBC), the most deadly type of breast cancer. By inhibiting a protein called …

Kella Vangsness (Photo by Cristy Lytal); featured image for USC’s Kella Vangsness paints stem cells as superheroes

USC’s Kella Vangsness paints stem cells as superheroes

With captions by Kella Vangsness “As an artist and scientist, I cannot help but imagine stem cells as ‘superheroes’ fighting against ‘villains’ of disease,” said Kella Vangsness, who is graduating from USC …

Kidney (Image by Lori O'Brien/Andy McMahon Lab, illustration by Mira Nameth)

Growing hope: New organs? Not yet, but stem cell research is getting closer

If you lose a limb, it’s lost for life. If you damage a kidney, you won’t grow a new one. And if you have a heart attack, the scars are there to …

Tubular networks developing in a mammalian kidney (Image by Tracy Tran/Andy McMahon Lab); featured image for Growing hope: What are stem cells, and how does USC use them?

Growing hope: What are stem cells, and how does USC use them?

Stem cell therapies have accelerated at a promising pace, but how do they work? And what are stem cells?

Justin Ichida (Photo by Ben Gibbs); featured image for USC Stem Cell scientist Justin Ichida named inaugural Richard N. Merkin Scholar

USC Stem Cell scientist Justin Ichida named inaugural Richard N. Merkin Scholar

In USC’s Department of Stem Cell Biology and Regenerative Medicine, half of the faculty members are assistant professors, poised at the threshold of their careers in biomedical research. One of these promising …

From left, stem cell researchers Andres Matias Lebensohn, Maxwell Z. Wilson, Seth Shipman, Pulin Li and Yejing Ge (Photo by Cristy Lytal); featured image for At USC’s Junior Faculty Mini-Symposium, stem cell scientists build to understand

At USC’s Junior Faculty Mini-Symposium, stem cell scientists build to understand

When physicist Richard Feynman died in 1988, he left a message scrawled across his chalkboard: “What I cannot create, I do not understand.” Twenty years later, scientists in a very different field …

At an early stage, a nephron forming in the human kidney generates an S-shaped structure. Green cells will generate the kidneys’ filtering device, and blue and red cells specialized regions responsible for distinct nephron activities. (Image courtesy of Stacy Moroz and Tracy Tran/McMahon Lab); featured image for Never accept a kidney donation from a mouse

Never accept a kidney donation from a mouse

Researchers are hard at work building mini-kidneys from human cells—using blueprints mostly drawn from lab mice. But mouse kidneys differ from their human counterparts in more than mere scale, as detailed by …

Joint cartilage (Image by Nancy Liu); featured image for Small molecule could make a big difference for arthritis patients

Small molecule could make a big difference for arthritis patients

Will there come a time when a patient with arthritis can forgo joint replacement surgery in favor of a shot? USC Stem Cell scientist Denis Evseenko has reason to be optimistic. In …

Motor nerve cells (Image courtesy of the Ichida Lab); featured image for The toxic relationship between ALS and frontotemporal dementia

The toxic relationship between ALS and frontotemporal dementia

ALS and frontotemporal dementia (FTD) are two neurodegenerative diseases with a toxic relationship, according to a new USC Stem Cell study published in Nature Medicine.

Green labels skeletal stem cells in the embryonic zebrafish head, and magenta labels the early-forming cartilaginous facial skeleton. (Video by Lindsey Barske/Crump Lab); featured image for USC Stem Cell scientists chew on the mysteries of jaw development

USC Stem Cell scientists chew on the mysteries of jaw development

Scientists in the USC Stem Cell laboratory of Gage Crump have revealed how key genes guide the development of the jaw in zebrafish. These findings may offer clues for understanding craniofacial anomalies …

Abigail Zamora; featured image for Broad Clinical Research Fellows use stem cells to build bone and combat cancer

Broad Clinical Research Fellows use stem cells to build bone and combat cancer

This year’s Broad Clinical Research Fellows will apply stem cell-based approaches to two prevalent problems: non-healing bone injuries, which affect 5 million Americans each year; and neuroblastoma, which is the most common …

Susana Cavallero (Photo by Cristy Lytal); featured image for USC scientist Susana Cavallero dedicates her heart to vascular stem cell research

USC scientist Susana Cavallero dedicates her heart to vascular stem cell research

Pursuing her passion for cardiovascular research, Susana Cavallero has journeyed from her hometown of Polvaredas in Saladillo, Argentina, to Buenos Aires to Los Angeles, where she is an assistant professor of research …

Michaela Patterson (Photo by Cristy Lytal); featured image for Broad Fellows look to stem cells to treat heart disease and hearing loss

Broad Fellows look to stem cells to treat heart disease and hearing loss

When it came time to select this year’s Broad Fellow, the award committee couldn’t pick just one. Instead, they bestowed the honor on two talented postdoctoral researchers in USC Stem Cell laboratories: …

From left, Rong Lu and Qi-Long Ying (Photo by Cristy Lytal); featured image for Broad Innovation Award winners work to develop cancer immunotherapy

Broad Innovation Award winners work to develop cancer immunotherapy

Imagine an ever-renewing source of immune cells that can be engineered to attack cancer and infections. The winners of this year’s Eli and Edythe Broad Innovation Award at USC are already striving …

Embryonic stem cells (Image/courtesy of Qi-Long Ying); featured image for Subtle cues can dictate the fate of stem cells

Subtle cues can dictate the fate of stem cells

If you’ve seen one GSK3 molecule, do not assume that you have seen them all. A new study in Developmental Cell reveals important differences in two similar forms of GSK3, which, in …

Embryonic mouse cortex with neural stem cells (red) and neurons (green) (Image by Wen-Hsuan Chang/Wange Lu Lab); featured image for Ryk needs a chaperone

Ryk needs a chaperone

Ryk has made the headlines by requiring a chaperone. But don’t assume that Ryk is a badly behaved celebrity—it’s actually a protein featured in a new study in the Proceedings of the …

Mouse rib cage stained to show cartilage (blue) and bone (red) (Image by Francesca Mariani); featured image for Mariani Lab reveals rules for making ribs

Mariani Lab reveals rules for making ribs

Scientists from the USC Stem Cell lab of Francesca Mariani recently shared a recipe for ribs, and it doesn’t even require barbecue sauce.