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Andy McMahon (Photo by Phil Channing); featured image for Hedgehog’s long snout finds a cure

Hedgehog’s long snout finds a cure

In 1993, the Human Frontier Science Program (HFSP) funded three researchers through one of the program’s prestigious Research Grants to work jointly on patterning of the mid-hindbrain region of the vertebrate embryo. …

Mouse femur with enchondroma-like structure (Image by Lick Lai); featured image for USC study reveals a protein that keeps people—and their skeletons—organized

USC study reveals a protein that keeps people—and their skeletons—organized

Most people think that their planners or their iPhones keep them organized, when proteins such as liver kinase b1 (Lkb1) actually have a lot more to do with it. New research from …

The study focused on tumors that can cause progressive enlargement of the jaw.; featured image for Healthy stem cells can create benign tumors in jaw

Healthy stem cells can create benign tumors in jaw

A new study from the Ostrow School of Dentistry of USC published in Cell Stem Cell illustrates how changes in cell signaling can cause ordinary stem cells in the jaw to start …

Staining of slow-cycling sweat gland cells (green) with the protein laminin (red) and the fluorescent stain DAPI (blue) (Image by Yvonne Leung); featured image for USC researcher learns how to break a sweat

USC researcher learns how to break a sweat

Without sweat, we would overheat and die. In a recent paper in the journal Public Library of Science One (PLOS ONE), USC faculty member Krzysztof Kobielak and a team of researchers explored …

Embryonic stem cells (Image/courtesy of Qi-Long Ying); featured image for USC researcher reveals how to better master stem cells’ fate

USC researcher reveals how to better master stem cells’ fate

USC scientist Qi-Long Ying and a team of researchers have long been searching for biotech’s version of the fountain of youth — ways to encourage embryonic stem cells (ESCs) and epiblast stem …

Yang Chai (Photo courtesy of the Ostrow School of Dentistry of USC); featured image for Ostrow School study links growth factor glitch to tongue defects

Ostrow School study links growth factor glitch to tongue defects

New findings about how cell signaling directs tongue development may have big clinical applications for healing tongue defects, according to an Ostrow School of Dentistry of USC study published in The Journal …

Compared with a normal zebrafish (top), this mutant (bottom) is a real bone head. (Image by Sandeep Paul and Seth Ruffins); featured image for Winner of the August 2013 USC Stem Cell Image of the Month Contest

Winner of the August 2013 USC Stem Cell Image of the Month Contest

Dr. Andrew McMahon and the judges of the USC Stem Cell Image of the Month contest would like to congratulate our August 2013 winners, Dr. Seth Ruffins and Sandeep Paul, a postdoc …

From left, Andrew P. McMahon, director of the Eli and Edythe Broad Center for Regenerative Medicine and Stem Cell Research, with Yong Chen’s son Gary and researcher Qi-Long Ying (Photo by Cristy Lytal); featured image for Businessman invests in stem cell research at USC

Businessman invests in stem cell research at USC

Chinese businessman Yong Chen has pledged $1 million to USC stem cell researcher Qi-Long Ying to support his future “eureka moments.” “When I talked to Mr. Chen, I told him that groundbreaking …

Neural stem cells derived from self-renewing mouse embryonic stem cells (Image courtesy of Qi-Long Ying); featured image for A special protein helps embryonic stem cells keep their options open

A special protein helps embryonic stem cells keep their options open

In the ongoing quest to understand how embryonic stem cells (ESCs) retain their ability to differentiate into virtually any kind of cell, USC faculty member Qi-Long Ying and a team of researchers …

From left, Gage Crump, Jay R. Lieberman and Francesca Mariani (Photo by Cristy Lytal); featured image for USC announces winners of first Regenerative Medicine Initiative awards

USC announces winners of first Regenerative Medicine Initiative awards

Three newly assembled disease teams within USC Stem Cell will take the early steps this year that might lead to future stem-cell based therapies for certain forms of deafness, bone defects and …

Songtao Shi, DDS, PhD (Photo courtesy of the Ostrow School of Dentistry of USC); featured image for Stem cells found in gum tissue can fight inflammatory disease

Stem cells found in gum tissue can fight inflammatory disease

Stem cells found in mouth tissue can not only become other types of cells but can also relieve inflammatory disease, according to a new Ostrow School of Dentistry of USC study in …

Wange Lu (Photo by Chris Shinn); featured image for USC study sheds light on stem cell reprogramming

USC study sheds light on stem cell reprogramming

Researchers are learning how to turn regular cells into stem cells, a process called reprogramming. However, some of the mechanisms of the process remain unknown, such as why only a small proportion of the cells can be reprogrammed. Researchers have at least part of the answer: the structure of genes.

Norman Arnheim; featured image for Common genetic disease linked to father’s age

Common genetic disease linked to father’s age

Scientists at USC have unlocked the mystery of why new cases of the genetic disease Noonan syndrome are so common—a mutation, which causes the disease, disproportionately increases a normal father’s production of …

Fanxin Long from Washington University School of Medicine; featured image for USC hosts mini-symposium on musculoskeletal development and repair

USC hosts mini-symposium on musculoskeletal development and repair

With its combination of bone, muscle, joints and more, the human musculoskeletal system is a complicated tangle of connections that can be difficult to repair. That was the challenge facing a panel …

Songtao Shi, DDS, PhD (Photo courtesy of the Ostrow School of Dentistry of USC); featured image for New method to treat chemo-related jaw bone necrosis

New method to treat chemo-related jaw bone necrosis

Over the last decade, osteonecrosis of the jaw (ONJ) has emerged as a devastating and debilitating condition of cancer patients receiving high doses of antiresorptive chemotherapy (bisphosphonates and denosumab). ONJ currently has …

From left to right: Mr. K.V. Kumar, Dr. Andy McMahon, Sir John Gurdon and Mr. Jonathan Thomas (Photo courtesy of USC); featured image for Interview with Sir John Gurdon

Interview with Sir John Gurdon

Sir John Gurdon, a Nobel Prize-winning biologist whose experiments in the field of cloning laid the foundation for modern stem cell research, visited the USC Health Sciences Campus on May 16. He …

Sir John Gurdon won the 2012 Nobel Prize in Physiology or Medicine for laying the groundwork for stem cell research. (Photo courtesy of John Gurdon); featured image for Nobel Laureate discusses history of cloning

Nobel Laureate discusses history of cloning

Cells can be stubborn things. A skin cell resists changing into a liver cell, and a heart cell wants to remain a heart cell. But with the right kind of manipulation, they …

American alligator skull (top); USC researchers identify three developmental phases for each alligator tooth unit, comprising a functional tooth (f), replacement tooth (r) and dental lamina (middle); a three-dimensional image of alligator tooth unit (bottom). (Photos courtesy of Cheng-Ming Chuong); featured image for Alligator stem cell study gives clues to tooth regeneration

Alligator stem cell study gives clues to tooth regeneration

Alligators may help scientists learn how to stimulate tooth regeneration in people, according to new research led by the Keck School of Medicine of USC. For the first time, a global team …

The cellular and molecular composition of feathers can be experimentally manipulated to test the hypothesis that certain molecular components may enhance or suppress pigment differentiation.; featured image for Birds of a feather flock together for stem cell research

Birds of a feather flock together for stem cell research

To eventually use stem cells in regenerative medicine, scientists need to understand how stem cells become organized into particular tissue patterns and shapes. With that in mind, researchers at USC recently found …

Professor Songtao Shi (Photo by John Skalicky); featured image for Ostrow School investigators recognized for research

Ostrow School investigators recognized for research

The International Association of Dental Research (IADR) honored two scientists from the Ostrow School of Dentistry of USC at the association’s general session opening ceremonies on March 20 in Seattle. Professor Songtao …