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A time-lapse shows the Wang Lab’s EchoBack CAR T-cells attacking a large tumor mass. The green labeled points are the tumor cells. (Image by Longwei Liu/Wang Lab); featured image for New “smart” immune cells: A breakthrough for long-lasting tumor destruction

New “smart” immune cells: A breakthrough for long-lasting tumor destruction

USC Viterbi researchers have engineered a new immune cell that when activated by ultrasound can continuously sense and destroy cancer cells for extended periods. Imagine a super-charged immune cell that can launch …

Müller glia (green) and their progeny (red) regenerate nerve cells and photoreceptors in a mouse retina (Image by Ksenia Gnedeva/USC); featured image for USC Stem Cell mouse study identifies shared genes involved in hearing and vision regeneration

USC Stem Cell mouse study identifies shared genes involved in hearing and vision regeneration

The same genes could hold the key to regenerating cells in the ear and eye, according to a new mouse study from the USC Stem Cell laboratory of Ksenia Gnedeva, published in …

Yali Dou, PhD, Marion and Harry Keiper Chair in Cancer Research at the Keck School of Medicine of USC, and associate director for basic research at USC Norris Comprehensive Cancer Center, has been elected an AAAS 2025 fellow. (Photo by Steve Cohn); featured image for AAAS elects Keck School of Medicine of USC molecular biologist Yali Dou as 2025 fellow

AAAS elects Keck School of Medicine of USC molecular biologist Yali Dou as 2025 fellow

Dou has broken new ground in the basic understanding of an enzyme that can cause leukemia and other cancers, and harnessed that knowledge at USC to develop potential therapies. Molecular biologist Yali …

Preet M. Chaudhary, MD, PhD, a professor of medicine, the Bloom Family Chair in Lymphoma Research, chief of the Nohl Division of Hematology (Photo courtesy of USC); featured image for Two USC innovators—Preet Chaudhary and Michael Selsted—honored by the National Academy of Inventors

Two USC innovators—Preet Chaudhary and Michael Selsted—honored by the National Academy of Inventors

Harnessing the body’s natural defenses, these researchers are advancing the future of immune-based treatments to develop breakthroughs in treating diseases ranging from rheumatoid arthritis and sepsis to cancer. Two researchers from the …

USC stem cell research center; featured image for 2025 Call for Applications: CIRM Clinical Research Fellowship in Stem Cell Biology and Regenerative Medicine

2025 Call for Applications: CIRM Clinical Research Fellowship in Stem Cell Biology and Regenerative Medicine

We have 1-year positions with a 1-year renewal option available for clinical trainees interested in conducting research related to stem cell biology and/or regenerative medicine in one of the leading labs at …

Tau protein in the brain of a mouse with a mutation that causes a common form of dementia (Image by Joshua Berlind/Ichida Lab/USC Stem Cell); featured image for How to clear the toxic tau protein that can lead to Alzheimer’s and related diseases

How to clear the toxic tau protein that can lead to Alzheimer’s and related diseases

USC Stem Cell scientists discover a new way to rid cells of toxic tau protein in a study involving mice and lab-grown human “mini-brains,” known as organoids. The neurotransmitter glutamate is essential …

Illustration of sound waves entering the ear (Image courtesy of iStock); featured image for Nerve fibers in the inner ear adjust sound levels and help compensate for hearing loss in mice, study finds

Nerve fibers in the inner ear adjust sound levels and help compensate for hearing loss in mice, study finds

Researchers from the Keck School of Medicine of USC, in collaboration with Baylor College of Medicine in Houston, Texas, used an innovative imaging tool to examine the mouse inner ear and made …

Pinchas Cohen; featured image for Gerontology Dean Pinchas Cohen named senior member of the National Academy of Inventors

Gerontology Dean Pinchas Cohen named senior member of the National Academy of Inventors

Cohen, an expert on mitochondrial microproteins and their therapeutic potential for diseases related to aging, holds several patents for novel peptides. Pinchas Cohen, Dean of the USC Leonard Davis School of Gerontology, …

A gene control element for human outer ear development shows activity in the gills (green) of a 2-week old zebrafish (Image by Mathi Thiruppathy/Crump Lab/USC Stem Cell); featured image for An earful of gill: USC Stem Cell study points to the evolutionary origin of the mammalian outer ear

An earful of gill: USC Stem Cell study points to the evolutionary origin of the mammalian outer ear

The outer ear is unique to mammals, but its evolutionary origin has remained a mystery. According to a new study published in Nature from the USC Stem Cell lab of Gage Crump, …

Ellis Meng, the Shelly and Ofer Nemirovsky Chair in Convergent Bioscience and professor of biomedical engineering and electrical and computer engineering (Photo courtesy of USC Viterbi); featured image for Revolutionizing heart care for newborns

Revolutionizing heart care for newborns

Ellis Meng’s team pioneers non-invasive shunt monitoring to improve survival rates for young patients with congenital heart defect. In pediatric cardiology, every heartbeat counts, especially for the one in 4,000 newborns born …

Eye (Image courtesy of iStock); featured image for Up to $47 million award supports collaborative eye transplant research co-led by USC

Up to $47 million award supports collaborative eye transplant research co-led by USC

An ambitious endeavor to restore sight unites the Keck School of Medicine of USC with the University of Colorado Anschutz Medical Campus and several other institutions from academia and beyond. A federal …

Caregiver with older woman (Image courtesy of iStock); featured image for USC selected to receive $3.4 million award from ARPA-H’s Sprint for Women’s Health

USC selected to receive $3.4 million award from ARPA-H’s Sprint for Women’s Health

The grant will fund Keck School of Medicine of USC research to test an innovative therapy to slow age-related cognitive decline. A team of researchers at The Keck School of Medicine of …

In the zebrafish inner ear, a cell type known as supporting cells (magenta) gives rise to new sensory hearing cells (blue). The study reveals a set of DNA control elements critical for supporting cells to regenerate hair cells after injury in zebrafish, lizards and other regenerative species. (Image by Tuo Shi/Crump and Lozito labs/USC Stem Cell); featured image for USC Stem Cell study breaks the silence on how fish and lizards regenerate hearing

USC Stem Cell study breaks the silence on how fish and lizards regenerate hearing

A new USC Stem Cell study published in the Proceedings of the National Academy of Sciences (PNAS) has identified key gene regulators that enable some deafened animals—including fish and lizards—to naturally regenerate …

Newborn neuron (green and purple cell) in brain tissue from patients with epilepsy (Image by Aswathy Ammothumkandy/Bonaguidi Lab/USC Stem Cell); featured image for To remember conversations, keep making new brain cells

To remember conversations, keep making new brain cells

USC-led study of patients with epilepsy shows how making new neurons benefits cognition in adults. Why do adults make new brain cells? A new study published in Cell Stem Cell provides the …

Brain illustration (Illustration by David Plunkett); featured image for Brilliant minds, healthy brains

Brilliant minds, healthy brains

USC brain researchers are finding novel ways to image, detect and treat diseases. This spring, scientists from the Keck School of Medicine of USC opened a new window into understanding the brain …

Illustration of man lifting weights by a refrigerator (Illustrations by Drue Wagner); featured image for Turn back the clock on aging

Turn back the clock on aging

There’s no way to stop the march of time, but innovative research by USC scholars points the way to a longer, healthier and more vibrant life. About 10 years ago, when George …

Illustrations by Doug Chayka; featured image for Cell by cell: Rebuilding the body

Cell by cell: Rebuilding the body

USC researchers are revolutionizing how we treat disease by harnessing stem cells as “living medicine.” Anyone who’s healed from a cut or a scrape has witnessed the incredible regenerative power of stem …

USC biomedical engineers have harnessed focused ultrasound to improve CRISPR, a revolutionary tool that enables the DNA in living organisms to be modified. (Image byWang Lab and Pepper Workshop); featured image for New CRISPR toolkit to allow remote-controlled genome editing

New CRISPR toolkit to allow remote-controlled genome editing

USC Viterbi biomedical engineers harness focused ultrasound to revolutionize CRISPR’s capabilities to treat countless diseases. Thanks to CRISPR, our medical specialists will soon have unprecedented control over how they treat and prevent …

Pinchas Cohen (left) in the lab (Photo courtesy of the USC Davis School of Gerontology); featured image for A powerhouse of innovation

A powerhouse of innovation

How a serendipitous discovery led by Pinchas Cohen more than 20 years ago opened a new chapter in biology and made the USC Leonard Davis School a leading force in unraveling the …

Eye (Image courtesy of iStock); featured image for $6 million grant drives potential treatment for common cause of vision loss toward the clinic

$6 million grant drives potential treatment for common cause of vision loss toward the clinic

The California Institute for Regenerative Medicine (CIRM) has funded Keck School of Medicine of USC translational research advancing a therapy for dry age-related macular degeneration, one of the leading causes of blindness …