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Motor nerve cells (Image courtesy of the Ichida Lab); featured image for The toxic relationship between ALS and frontotemporal dementia

The toxic relationship between ALS and frontotemporal dementia

ALS and frontotemporal dementia (FTD) are two neurodegenerative diseases with a toxic relationship, according to a new USC Stem Cell study published in Nature Medicine.

Diffusion MRI maps show disrupted white matter connectivity and loss of white matter fiber tracts in 1 year-old pericyte-deficient mice. (Image courtesy of the Zlokovic Lab); featured image for Half of all dementias start with damaged “gatekeeper cells”

Half of all dementias start with damaged “gatekeeper cells”

USC research sheds new light on how a breakdown in the brain’s vascular system predates the accumulation of toxic plaques and tangles in the brain that bring about Alzheimer’s disease. The research …

Valter Longo (Photo by John Skalicky); featured image for What to know about fasting, aging, the “longevity diet” and when you should eat

What to know about fasting, aging, the “longevity diet” and when you should eat

Biochemist Valter Longo has devoted decades to discovering connections between nutrition and successful aging. He runs the Longevity Institute at the USC Leonard Davis School of Gerontology, which aims to extend healthy …

Bérénice Benayoun (Photo courtesy of the USC Davis School of Gerontology); featured image for Bérénice Benayoun studies possibility of rejuvenating genes

Bérénice Benayoun studies possibility of rejuvenating genes

Bérénice Benayoun, assistant professor at the USC Leonard Davis School of Gerontology and principal investigator with USC Stem Cell, explores the role of epigenetics—the ways that genes turn “off” or “on”—in the …

Green labels skeletal stem cells in the embryonic zebrafish head, and magenta labels the early-forming cartilaginous facial skeleton. (Video by Lindsey Barske/Crump Lab); featured image for USC Stem Cell scientists chew on the mysteries of jaw development

USC Stem Cell scientists chew on the mysteries of jaw development

Scientists in the USC Stem Cell laboratory of Gage Crump have revealed how key genes guide the development of the jaw in zebrafish. These findings may offer clues for understanding craniofacial anomalies …

Malcolm Snead (Photo courtesy of the Ostrow School of Dentistry of USC); featured image for USC professor Malcolm Snead elected to AIMBE College of Fellows

USC professor Malcolm Snead elected to AIMBE College of Fellows

Malcolm Snead, a professor at the Ostrow School of Dentistry of USC and a principal investigator with USC Stem Cell, has been elected to the American Institute for Medical and Biological Engineering …

(Image courtesy of the Keck School of Medicine of USC); featured image for Deep sea creatures provide a guiding light in the quest to develop cancer-fighting therapies

Deep sea creatures provide a guiding light in the quest to develop cancer-fighting therapies

A team of scientists at the Keck School of Medicine of USC is looking to some deep sea dwellers to create a better way to develop cancer-fighting therapies. Harnessing the power of …

Synapses between nerve cells, called neurons, and muscle cells in the fruit fly Drosophila are giving clues to how neurons maintain communication. Here, a synapse is immunostained with antibodies that recognize the neuronal membrane (blue), active zones (green) and neurotransmitter receptors (red). (Image courtesy of Dion Dickman); featured image for Answers for diseases like schizophrenia may lie in how the brain maintains balance

Answers for diseases like schizophrenia may lie in how the brain maintains balance

Pop psychologists tout “balance” as key to mental health, and they may be more right than they realize. Neuroscientist Dion Dickman is gaining insight into how the brain maintains healthy balance on …

Abigail Zamora; featured image for Broad Clinical Research Fellows use stem cells to build bone and combat cancer

Broad Clinical Research Fellows use stem cells to build bone and combat cancer

This year’s Broad Clinical Research Fellows will apply stem cell-based approaches to two prevalent problems: non-healing bone injuries, which affect 5 million Americans each year; and neuroblastoma, which is the most common …

Susana Cavallero (Photo by Cristy Lytal); featured image for USC scientist Susana Cavallero dedicates her heart to vascular stem cell research

USC scientist Susana Cavallero dedicates her heart to vascular stem cell research

Pursuing her passion for cardiovascular research, Susana Cavallero has journeyed from her hometown of Polvaredas in Saladillo, Argentina, to Buenos Aires to Los Angeles, where she is an assistant professor of research …

Michaela Patterson (Photo by Cristy Lytal); featured image for Broad Fellows look to stem cells to treat heart disease and hearing loss

Broad Fellows look to stem cells to treat heart disease and hearing loss

When it came time to select this year’s Broad Fellow, the award committee couldn’t pick just one. Instead, they bestowed the honor on two talented postdoctoral researchers in USC Stem Cell laboratories: …

Laura Perin (Photo courtesy of CHLA); featured image for New cellular approach found to control progression of chronic kidney disease

New cellular approach found to control progression of chronic kidney disease

Researchers have demonstrated for the first time that extracellular vesicles—tiny protein-filled structures—isolated from amniotic fluid stem cells (AFSCs) can be used to effectively slow the progression of kidney damage in mice with …

From left, Rong Lu and Qi-Long Ying (Photo by Cristy Lytal); featured image for Broad Innovation Award winners work to develop cancer immunotherapy

Broad Innovation Award winners work to develop cancer immunotherapy

Imagine an ever-renewing source of immune cells that can be engineered to attack cancer and infections. The winners of this year’s Eli and Edythe Broad Innovation Award at USC are already striving …

Embryonic stem cells (Image/courtesy of Qi-Long Ying); featured image for Subtle cues can dictate the fate of stem cells

Subtle cues can dictate the fate of stem cells

If you’ve seen one GSK3 molecule, do not assume that you have seen them all. A new study in Developmental Cell reveals important differences in two similar forms of GSK3, which, in …

Joycelyn Yip says she wishes she could have five different careers. (Photo by Susanica Tam); featured image for Creating new heart muscle out of stem cells? This grad student is doing it

Creating new heart muscle out of stem cells? This grad student is doing it

In a narrow room not much larger than a closet, Joycelyn Yip reaches behind a glass shield to lower a pipette to a plate of silicon-coated glass. Swaddled in a sterile white …

Embryonic mouse cortex with neural stem cells (red) and neurons (green) (Image by Wen-Hsuan Chang/Wange Lu Lab); featured image for Ryk needs a chaperone

Ryk needs a chaperone

Ryk has made the headlines by requiring a chaperone. But don’t assume that Ryk is a badly behaved celebrity—it’s actually a protein featured in a new study in the Proceedings of the …

Mouse rib cage stained to show cartilage (blue) and bone (red) (Image by Francesca Mariani); featured image for Mariani Lab reveals rules for making ribs

Mariani Lab reveals rules for making ribs

Scientists from the USC Stem Cell lab of Francesca Mariani recently shared a recipe for ribs, and it doesn’t even require barbecue sauce.

From left, Gio Suh and Lauren Ekman (Photo by Cristy Lytal); featured image for Countdown to Commencement: Gio Suh builds muscles without exercising

Countdown to Commencement: Gio Suh builds muscles without exercising

“I’ve always wanted to be in a textbook and impact the world,” said Gio Suh, who is graduating in December 2017 from the master of science program in stem cell biology and …

David Warburton (Photo courtesy of Children's Hospital Los Angeles)

David Warburton among USC professors named fellows of esteemed scientific society

Five USC scientists and one Keck School of Medicine of USC physician have been elected fellows of the American Association for the Advancement of Science, an honor awarded to AAAS members by …

Immune cells (highlighted in yellow) in the mouse colon that are the proposed target of TNFR2-activating therapy in inflammatory bowel disease (IBD) (Image courtesy of D. Brent Polk); featured image for Study to examine how tumor necrosis factor works to reduce intestinal inflammation

Study to examine how tumor necrosis factor works to reduce intestinal inflammation

D. Brent Polk, MD, AGAF, an investigator at Children’s Hospital Los Angeles, has been awarded $1.5 million by the National Institute of Diabetes and Digestive and Kidney Diseases of the NIH for …