Is this the gamechanger we’ve been waiting for in craniosynostosis?
One of our every 2,500 infants born in the United States will suffer from craniosynostosis — a craniofacial defect caused by the premature fusion of the different bones that comprise the human …
Stem cells may correct deformity and restore brain function after childhood disorder
USC scientists have regenerated parts of the skull affected by a common birth defect called craniosynostosis. Using stem cells to regenerate parts of the skull, USC scientists partially corrected a skull deformity …
USC Stem Cell PhD Student Ruzanna “Rose” Shkhyan works to end inflamm-aging
USC PhD student Ruzanna “Rose” Shkhyan has gotten a first-hand look at how stem cell discoveries can lead to clinical trials. As member of the USC Stem Cell laboratory of Denis Evseenko, …
USC Stem Cell scientist Giorgia Quadrato receives a 2020 Mallinckrodt Grant
Giorgia Quadrato, an assistant professor in USC’s Department of Stem Cell Biology and Regenerative Medicine, was recently awarded an Edward Mallinckrodt Foundation (EMF) grant to further her research about modeling human brain …
Can COVID-19 cause diabetes?
Can the novel coronavirus—SARS-CoV-2—cause diabetes? No one knows, but Senta Georgia, PhD, is trying to find out. Dr. Georgia, an investigator in The Saban Research Institute of Children’s Hospital Los Angeles, recently …
Flaws emerge in modeling human genetic diseases in animals
My lab, based at the University of Southern California Keck School of Medicine, uses zebrafish to model human birth defects affecting the face. When I tell people this, they are often skeptical …
Brain development and disorder research receives $1.5 million NSF boost
The human brain is an incredibly complex organ to study in its living tissue form. Researchers cannot experiment on human tissue directly, and animal models are often too different to human physiology …
A high-tech look at rejection in pediatric liver transplants
Surgeon-scientist Juliet Emamaullee, MD, PhD, spends much of her time seeing patients and performing pediatric liver transplants at Children’s Hospital Los Angeles. But you’ll also find her in the lab—studying how to …
Happy 10th anniversary to USC’s stem cell research center
On October 29, 2010, we opened the doors of the Eli and Edythe Broad CIRM Center for Regenerative Medicine and Stem Cell Research at USC. Today, on the 10th anniversary of the …
USC pediatric surgeon aims to heal infants using stem cells
Tracy Grikscheit helps babies with digestive disorders. Stem cells could help her develop life-changing treatments. It’s an instinct many surgeons have: Whatever you have to remove, replace it with something better. Something …
Treatment for Inflammatory bowel disease doesn’t always work; new study uncovers why
Inflammatory bowel disease (IBD) affects more than 70,000 children in the United States and the prevalence is rising. In fact, 25% of the 3.1 million individuals with IBD present before 21 years …
Pituitary puzzle gets a new piece, revising evolutionary history
Insights into century-old controversy about key gland’s development arise from research led by the Keck School of Medicine of USC A new USC-led study suggests a change to the developmental — and …
USC biological imaging innovator elected to National Academy of Medicine
Scott Fraser, Provost Professor of Biological Sciences, Biomedical Engineering, Physiology and Biophysics, Stem Cell Biology and Regenerative Medicine, Pediatrics, Radiology and Ophthalmology, has been elected to the National Academy of Medicine. Fraser, …
A bench-to-bedside approach to Wilms tumor
Stefano Da Sacco, PhD, calls Wilms tumor “an underdog” in the research world. “If you go to the American Urological Association or other meetings, there aren’t many presentations or discussions about Wilms …
California’s biggest stem cell experiment: The impact of the stem cell ballot proposition at USC
In 2008, USC broke ground on an $80 million building dedicated solely to stem cell research and regenerative medicine. The plans called for a monolithic structure clad in black marble and reflective …
USC’s Scott E. Fraser elected to National Academy of Medicine
USC biophysicist Scott E. Fraser, PhD, has as been elected to the National Academy of Medicine, the organization announced Monday. He’s among 100 new members of the Academy. “For integrating biophysics, quantitative …
When it comes to arthritic bone spurs, stem cells hurt instead of heal
The same stem cells that heal broken bones can also generate arthritic bone spurs called osteophytes, according to a new study in the Annals of Rheumatic Diseases. “Although these stem and progenitor …
The childhood moments that launched their careers as explorers
Innocent curiosity can turn discovery into life’s purpose. A toddler locks eyes with a turtle for the first time; a mischievous teen concocts stink bombs in the garage. However their careers develop, …
USC-led study traces the evolution of gill covers
The emergence of jaws in primitive fish allowed vertebrates to become top predators. What is less appreciated is another evolutionary innovation that may have been just as important for the success of …
USC-led research team shares 10 years’ progress in collecting data to push craniofacial science forward
It has been a little more than a decade since the National Institute of Dental and Craniofacial Research (NIDCR) launched FaceBase, a central repository for craniofacial datasets and tools meant to advance …