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Wange Lu (Photo by Chris Shinn); featured image for USC study sheds light on stem cell reprogramming

USC study sheds light on stem cell reprogramming

Researchers are learning how to turn regular cells into stem cells, a process called reprogramming. However, some of the mechanisms of the process remain unknown, such as why only a small proportion of the cells can be reprogrammed. Researchers have at least part of the answer: the structure of genes.

From left to right: Mr. K.V. Kumar, Dr. Andy McMahon, Sir John Gurdon and Mr. Jonathan Thomas (Photo courtesy of USC); featured image for Interview with Sir John Gurdon

Interview with Sir John Gurdon

Sir John Gurdon, a Nobel Prize-winning biologist whose experiments in the field of cloning laid the foundation for modern stem cell research, visited the USC Health Sciences Campus on May 16. He …

Sir John Gurdon won the 2012 Nobel Prize in Physiology or Medicine for laying the groundwork for stem cell research. (Photo courtesy of John Gurdon); featured image for Nobel Laureate discusses history of cloning

Nobel Laureate discusses history of cloning

Cells can be stubborn things. A skin cell resists changing into a liver cell, and a heart cell wants to remain a heart cell. But with the right kind of manipulation, they …

Sir John Gurdon won the 2012 Nobel Prize in Physiology or Medicine for laying the groundwork for stem cell research. (Photo courtesy of John Gurdon); featured image for Nobel laureate to speak on stem cells at HSC

Nobel laureate to speak on stem cells at HSC

Nobel laureate Sir John Gurdon will speak on “From Nuclear Transplantation to Prospects for Cell Replacement” on May 16 at noon in the Aresty Auditorium of the Harlyne J. Norris Cancer Research …

Andy McMahon (Photo by Phil Channing); featured image for Probing the power of stem cells

Probing the power of stem cells

Piece by missing piece, scientists at the Keck School of Medicine of USC are deciphering the powerful gene regulatory circuit that maintains and controls the potential of embryonic stem cells (ESCs) to …

Dr. Wange Lu and Fan Gao (Photo courtesy of USC); featured image for Unraveling the mystery of pluripotency in embryonic stem cells

Unraveling the mystery of pluripotency in embryonic stem cells

Using advanced sequencing technology, USC Stem Cell faculty member Wange Lu, in collaboration with Kai Wang of the USC Zilkha Neurogenetics Institute, explores the mystery of pluripotency by mapping out the interaction …

Andy McMahon (Photo by Phil Channing); featured image for McMahon discusses central role of stem cell biology in medicine of the future

McMahon discusses central role of stem cell biology in medicine of the future

USC scored a major coup when it brought scientist Andrew McMahon to the Keck School of Medicine of USC from Harvard University, where he had served for almost two decades as a …

Dr. Qilong Ying (left) and USC graduate student Chih-I (Jimmy) Tai (Photo courtesy of USC); featured image for An important factor identified in reprogramming

An important factor identified in reprogramming

How is the stem cell state programmed? A new study in Qi-Long Ying’s group at the Eli and Edythe Broad Center for Regenerative Medicine and Stem Cell Research at USC highlights the role …

Stem cells (Image courtesy of Justin Ichida); featured image for USC launches Regenerative Medicine and Stem Cell Research Initiative

USC launches Regenerative Medicine and Stem Cell Research Initiative

A new USC initiative has been introduced to support collaborative research in regenerative medicine and stem cell biology across the university, facilitating the critical move from basic research into clinical applications.

The Chronicle of Higher Education featured an article about USC's recruitment of Scott Fraser.

Chronicle of Higher Education features Scott Fraser

The Chronicle of Higher Education featured Scott Fraser, Provost Professor of Biological Sciences and Biomedical Engineering and the Director of Science Initiatives at USC, who arrived this year from the California Institute …

The cover of Developmental Cell features "S1P Receptor Constrains Angiogenesis."

In trio of studies, USC researcher examines biochemical pathways

In his brief tenure as director of the Eli and Edythe Broad Center for Regenerative Medicine and Stem Cell Research at USC, Andrew McMahon has published three articles, in two key areas of …

Scott Fraser, a world leader in using advanced technologies to capture biological processes (Photo by John Livzey); featured image for Scott Fraser named Provost Professor at USC

Scott Fraser named Provost Professor at USC

Elizabeth Garrett, USC provost and senior vice president for academic affairs, has announced the appointment of Scott Fraser as Provost Professor of Biological Sciences and Biomedical Engineering and the Director of Science …

Andy McMahon (Photo by Phil Channing); featured image for Andrew McMahon installed as chair of stem cell biology at Keck School of Medicine of USC

Andrew McMahon installed as chair of stem cell biology at Keck School of Medicine of USC

Andrew P. McMahon, newly appointed department chair of stem cell biology and regenerative medicine at the Keck School of Medicine of USC and director of the Eli and Edythe Broad Center for …

Andy McMahon (Photo by Phil Channing); featured image for California Institute for Regenerative Medicine awards USC researcher $5.7 million

California Institute for Regenerative Medicine awards USC researcher $5.7 million

California’s stem cell agency, the California Institute for Regenerative Medicine (CIRM) has approved $5.7 million for a USC researcher to help move promising stem cell-based therapies from the laboratory research phase to …

Andy McMahon (Photo by Phil Channing); featured image for Harvard scientist recruited to lead USC’s center for stem cell research and regenerative medicine

Harvard scientist recruited to lead USC’s center for stem cell research and regenerative medicine

The University of Southern California announces a major scientific recruitment to the Keck School of Medicine, one that will have a transformative effect on the medical and biological sciences across the university’s …

Stem cell (Creative Commons image by Reuters); featured image for USC scientists find mechanism that allows for reprogramming stem cells

USC scientists find mechanism that allows for reprogramming stem cells

In healthy bodies, liver cells beget liver cells, while skin cells beget skin cells. Previous research, however, has shown that—sometimes—cells can be reprogrammed, from skin, for example, to muscle or vice versa. …

Qi-Long Ying (Photo by Cristy Lytal); featured image for USC research listed among top breakthroughs of 2010

USC research listed among top breakthroughs of 2010

Groundbreaking research by Keck School of Medicine of USC researchers has been selected as one of Science magazine’s top 10 Breakthroughs of 2010. The study, Production of p53 gene knockout rats by …

Qi-Long Ying (Photo by Cristy Lytal); featured image for USC researchers create first “knockout” rats using embryonic stem cell technology

USC researchers create first “knockout” rats using embryonic stem cell technology

Researchers at the Keck School of Medicine of the University of Southern California (USC) have, for the first time, generated “knockout” rats—animals that are genetically modified to lack one or more genes—through …