Dr. McMahon’s laboratory explores the mechanisms that maintain stem/progenitor cells and regulate their differentiation to mature cell types of different organ systems, particularly the kidney. By combining genetic and genomic approaches with high resolution imaging, his group is aiming to obtain a deeper understanding of stem cell biology and to develop novel therapeutic strategies for regenerative medicine.
Stories
Four honored at UKRO benefit gala
University Kidney Research Organization (UKRO) honored USC academic and scientific leaders at its sixth gala dinner March 18 at The Beverly Hilton, with 300 attendees. This group of vocal champions of kidney …
USC researchers discover a key difference between mouse and human kidney stem cells
The best laid plans of mice and men are a bit different — at least when it comes to kidney development. Compared to a mouse, a human has nearly 100 times more nephrons, …
USC Stem Cell mini-symposium introduces next-generation researchers
The next generation of scientists is turning to stem cells to advance our understanding of systems ranging from the blood to the brain, from the liver to the lungs. Six of these …
UKRO benefit dinner to honor USC leaders
University Kidney Research Organization (UKRO) will honor a stellar group of USC academic and scientific leaders at its sixth gala dinner on March 18 at The Beverly Hilton. This group of vocal …
USC announces winners of the Audrey E. Streedain Regenerative Medicine Initiative Awards
Two collaborative teams within USC Stem Cell are developing new approaches that could eventually help patients with heart disease, frontotemporal dementia and amyotrophic lateral sclerosis (ALS). The teams are the winners of …
At Keck-Dornsife retreat, scientists share research
Seeking to strengthen partnerships between two of USC’s oldest schools, scientists from the Keck School of Medicine of USC and USC Dornsife College of Letters, Arts and Sciences recently gathered to discuss …
Postdoctoral fellow Albert Kim receives first Hearst Fellowship
How do you turn stem cells into nephrons, the functional unit of the kidney? Albert D. Kim, a postdoctoral fellow in the laboratory of Andy McMahon, is exploring this question with support …
Chang Stem Cell Engineering Facility brings gene editing to USC and beyond
Once the stuff of science fiction, genetic engineering is now offered on a fee-for-service basis at USC. On September 19, USC Stem Cell faculty and staff welcomed their supporters, the Chang and …
Gene summons “surviving cells on deck” to repair the acutely injured kidney
In the kidney, injured cells can be kicked into reparative mode by a gene called Sox9, according to a new paper published in Cell Reports. First author Sanjeev Kumar, a postdoctoral research …
USC/UKRO Kidney Research Center opening is held
Keck School of Medicine of USC researchers recently joined board members from the University Kidney Research Organization (UKRO) to celebrate the opening of the USC/UKRO Kidney Research Center in the Mudd Memorial …
USC Stem Cell selects inaugural Broad Clinical Research Fellows
This year, the Broad Clinical Research Fellowships are enabling physician-investigators to explore stem cell-based approaches related to four very different medical conditions: breast cancer, kidney disease, deafness and short bowel syndrome. Each …
USC kidney researcher Janos Peti-Peterdi wins Young Investigator Award
USC kidney researcher Janos Peti-Peterdi has been selected as the 2015 recipient of the ASN-AHA Young Investigator Award. Co-sponsored by the American Society of Nephrology (ASN) and the Council on the Kidney …
The Merkin Family Foundation establishes four assistant professorships in regenerative medicine at USC
In the past two years, USC’s Department of Stem Cell Biology and Regenerative Medicine has welcomed six new assistant professors to its ranks — and more are on the horizon. Thanks to a …
USC Stem Cell researchers reveal a genetic blueprint for cartilage
Cartilage does a lot more than determine the shapes of people’s ears and noses. It also enables people to breathe and to form healthy bones — two processes essential to life. In …
Engineering undergraduates focus on building a microscope for USC’s stem cell research center
Previously, when Andy McMahon, head of USC Stem Cell, wanted a three-dimensional image of a kidney, he would ship the organ to Australia. Now, he can send the organ down the hall …
Tri-institutional Stem Cell Retreat brings together Broad centers from USC, UCLA and UCSF
Working alone, a scientist or university can only make so much progress in finding answers to basic questions or new treatments for diseases ranging from HIV to cancer to diabetes. That’s why …
Take a tour of USC’s stem cell research center
Video by Alric Devotta Director Andy McMahon leads a tour of the Eli and Edythe Broad CIRM Center for Regenerative Medicine and Stem Cell Research at USC.
USC summit marks rebirth of biotech era in Los Angeles
Los Angeles city and county policymakers and educational institutions laid the groundwork for the region’s biotechnology strategy at a summit on the USC Health Sciences Campus. The Los Angeles Biotech Summit drew …
USC Stem Cell Symposium creates scientific synergy
Provost Michael Quick convened the inaugural USC Stem Cell Symposium with a straightforward truth about the future of regenerative medicine: “it will take a dedicated community of scholars across the disciplines to …
USC hosts California stem cell agency’s tenth birthday bash
Few 10 year olds have brought 10 potential medical treatments into clinical trials. The California Institute for Regenerative Medicine (CIRM), however, is a truly exceptional 10 year old. In 2004, the people …