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Red indicates mouse embryonic stem cells and green indicates mouse epiblast stem cells. The two cell types were co-cultured under GSK3α inhibition and maintained their distinct identities. (Image by Duo Wang/Ying Lab/USC Stem Cell); featured image for A “stemness checkpoint” helps control stem cell identity

A “stemness checkpoint” helps control stem cell identity

Building on the concept that blocking differentiation into specialized cell types maintains stem cells, USC and NIH scientists identify GSK3α as a checkpoint across diverse stem cell types. A study published in …

Clockwise from top left, Paula Cannon, Alan Epstein, Heinz-Josef Lenz and Bodour Salhia (Photos by Don Milici and Ricardo Carrasco III); featured image for Four Keck School of Medicine of USC researchers elected as senior members of the National Academy of Inventors

Four Keck School of Medicine of USC researchers elected as senior members of the National Academy of Inventors

Honorees have created technologies for fighting cancer and other diseases by harnessing the immune system, DNA and the mechanisms that control gene expression. The National Academy of Inventors (NAI), a nonprofit member …

Mohamed Abou-el-Enein and Amaia Cadinanos-Garai (Photo by Anson Cheung); featured image for USC physician-scientist Mohamed Abou-el-Enein named Outstanding New Investigator by the American Society of Gene + Cell Therapy

USC physician-scientist Mohamed Abou-el-Enein named Outstanding New Investigator by the American Society of Gene + Cell Therapy

In addition, Abou-el-Enein, lab member Amaia Cadinanos-Garai and their co-authors received the Best of Molecular Therapy Award for their paper describing a new tool for identifying which CAR T cells are best …

PhD student Connor Fausto at Stem Cell Day (Photo by Wayne Lewis); featured image for Stem Cell Day demystifies the world of science for high school students

Stem Cell Day demystifies the world of science for high school students

With support from the California Institute for Regenerative Medicine (CIRM), USC Stem Cell welcomes teens to campus for education and outreach that opens their eyes to future career possibilities. The buzzer chimed, …

The new joint department will accelerate health care innovation. (USC Photos); featured image for USC announces joint biomedical engineering department, bridging medical and engineering schools

USC announces joint biomedical engineering department, bridging medical and engineering schools

Building on decades of collaboration between the USC Viterbi School of Engineering and the Keck School of Medicine of USC, the department reimagines the expansion of biomedical engineering into medicine. The Keck …

Photo: iStock; featured image for USC receives funding for AI tool to advance treatment for rare pediatric diseases

USC receives funding for AI tool to advance treatment for rare pediatric diseases

With up to $6.8 million in funding, USC researchers will develop an AI-driven framework to strengthen how evidence is generated for gene and cell therapies, helping to bring promising treatments closer to …

Wynnie Nguyen (Photo by Mohammad Shariq); featured image for USC Stem Cell doctoral student Wynnie Nguyen aims to shift paradigms in Alzheimer’s research

USC Stem Cell doctoral student Wynnie Nguyen aims to shift paradigms in Alzheimer’s research

Nguyen was awarded a grant from the Cure Alzheimer’s Fund for studies aiming to stimulate growth of new brain cells and, ultimately, reverse the course of dementia. For USC Stem Cell PhD …

Pipetting in the lab; featured image for Meet the scholarship recipients in USC’s stem cell master’s program

Meet the scholarship recipients in USC’s stem cell master’s program

Four scholarship recipients combine medicine with mentorship and science with service. From authoring a bilingual STEM coloring book to mentoring biotechnology students at Los Angeles Mission College, this year’s scholarship recipients in …

From left, USC researchers John Oghalai, MD, and Alberto Recio, PhD (Image courtesy of the USC Caruso Department of Otolaryngology–Head and Neck Surgery); featured image for Exploring how the cochlea responds to speech sounds: John Oghalai and Alberto Recio receive an American Hearing Research Foundation (AHRF) Discovery Grant

Exploring how the cochlea responds to speech sounds: John Oghalai and Alberto Recio receive an American Hearing Research Foundation (AHRF) Discovery Grant

The one-year grant will support research on how the cochlea responds to fricative consonants like “S” and “SH.” USC researchers John Oghalai, MD, and Alberto Recio, PhD, were inspired by a simple …

Concept art depicts a cross-section of the intestine, its folds interwoven with leafy forms symbolizing the complex and dynamic microbial ecosystem within. Surrounding the gut are ovarian histology images spanning different ages, representing the progressive structural changes that accompany ovarian aging. Together, the imagery reflects the bidirectional dialogue between the gut and the ovary and highlights the potential of the microbiome as a lever to reshape the trajectory of reproductive aging. (Illustration by Rapheal Williams, Benayoun Laboratory); featured image for Fecal transplants from older mice significantly improve ovarian function and fertility in younger mice

Fecal transplants from older mice significantly improve ovarian function and fertility in younger mice

The surprising findings shed light on the little-known relationship between the microbiome and the reproductive system. Greater understanding could lead to better treatment options not only for fertility but also for overall …

Ksenia Gnedeva (Photo by Cristy Lytal); featured image for Recognizing promise in hearing research: Ksenia Gnedeva wins the 2026 Geraldine Dietz Fox Young Investigator Award

Recognizing promise in hearing research: Ksenia Gnedeva wins the 2026 Geraldine Dietz Fox Young Investigator Award

The Association for Research in Otolaryngology recognizes Gnedeva for her work in understanding the development and regeneration of the inner ear’s sensory hearing cells. As Ksenia Gnedeva, PhD, was finishing her postdoctoral …

Eric Schulze, PhD (Photo by Kate Warren); featured image for Science benefiting society: Evergreen Select CTO got his start with PhD in USC Stem Cell lab

Science benefiting society: Evergreen Select CTO got his start with PhD in USC Stem Cell lab

From USC biomedical labs to D.C. to a Bay Area startup, Eric Schulze makes a difference thanks to career-oriented doctoral education at the Keck School of Medicine of USC. Eric Schulze has …

(Image courtesy of Adobe Stock); featured image for New stem cell treatment may offer hope for Parkinson’s disease

New stem cell treatment may offer hope for Parkinson’s disease

Keck Medicine of USC investigates a unique therapy that aims to repair damaged brain cells Parkinson’s disease is a progressive neurodegenerative disorder that affects more than one million people in the United …

When not juggling the myriad tasks required as Ostrow's newest Dean, Yang Chai feels most at peace, cultivating the gardens at his L.A. home. (Photo by Christina Gandolfo)

Growing a garden of academic excellence

His path to USC from China led the clinician-scientist through resilience and growth — and now the Ostrow Dean will nurture learning, patient care and research into the future. On Sundays, Ostrow’s …

Hands holding landscape iPad; featured image for New federal grant to help researchers explore better treatment options for temporomandibular disorders

New federal grant to help researchers explore better treatment options for temporomandibular disorders

The $4.3-million NIDCR grant will help clinicians build upon previous work to improve patient outcomes for those suffering with TMD pathology. There are few joints as complex as the jaws — they …

Megan McCain's lab (Photo by Chris Shinn)

USC launches a new Center for Stem Cell Engineering on the Health Sciences Campus

A collaboration between the Keck School of Medicine of USC and the USC Viterbi School of Engineering, the center will use stem cell engineering to uncover disease mechanisms and advance new therapies. …

An implantable retinal patch for restoring vision is one of the university’s most cited examples of therapeutic success. (Illustration/aDerek Brahney); featured image for From lab to launch: Inside USC’s fast-growing ecosystem of health startups

From lab to launch: Inside USC’s fast-growing ecosystem of health startups

From patches that restore vision to compounds that kill brain tumors, drug and device discoveries by USC researchers are reaching patients faster than ever before. Ten years ago, two pediatric heart specialists …

Stem cell-derived patch (Photo courtesy of Regenerative Patch Technologies LLC); featured image for Can a retinal implant reverse macular degeneration?

Can a retinal implant reverse macular degeneration?

Clinical trial explores if stem cell-derived patch can help replace cells damaged by the disease and restore vision. Age-related macular degeneration, the leading cause of vision loss and blindness for Americans 65 …

Stable communication between neurons is key to overall brain health and muscle control. (Image courtesy of iStock); featured image for Biologists discover neurons use physical signals — not electricity — to stabilize communication

Biologists discover neurons use physical signals — not electricity — to stabilize communication

A USC Dornsife team shows how synapses rapidly adjust when their receptors fail, revealing a new mechanism of neural resilience. Every movement you make and every memory you form depends on precise …

Chuck Murry in the third-grade class at Vermont Avenue Elementary School (Photo by DJ Kast); featured image for USC Stem Cell’s Chuck Murry shows heart for local third-graders through the medical and cancer STEM programs

USC Stem Cell’s Chuck Murry shows heart for local third-graders through the medical and cancer STEM programs

USC’s Medical STEM Program brings pig hearts, pulse oximeters, and a world of possibility to local third graders. At Vermont Avenue Elementary School, a class of third graders stared wide-eyed as Chuck …